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Male Germline Chromatin



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Autore: Griffin Darren Visualizza persona
Titolo: Male Germline Chromatin Visualizza cluster
Pubblicazione: Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020
Descrizione fisica: 1 electronic resource (144 p.)
Soggetto topico: Research & information: general
Biology, life sciences
Soggetto non controllato: mouse sperm chromatin
chromosome organization
nuclear-3D-parameters
spermiogenesis
chromatin remodeling
DNA double-strand breaks
genetic instability
mutations
sperm DNA damage
DNA fragmentation
infertility
assisted reproduction
miscarriage
implantation
nuclear organization
sperm
morphometrics
chromosome painting
nucleoli
NOR
chromosome associations
meiotic prophase
spermatocytes
Mus m. domesticus
Robertsonian chromosomes
chromosome translocation
Y chromosome
testis
spermatogenesis
SLY
mouse
oxidative stress
reactive oxygen species
chromatin
DNA oxidation
male infertility
spermatozoa
chromosomes
chromosome territories
centromeres
male germ cells
telomeres
reproductive aging
nuclear organisation
epigenetic inheritance
histone retention
in vitro fertilisation
Persona (resp. second.): EllisPeter
GriffinDarren
Sommario/riassunto: Spermatogenesis requires radical restructuring of germline chromatin at multiple stages, involving coordinated waves of DNA methylation/demethylation, histone modification, and the replacement and removal that occurs before, during, and after meiosis. This Special Issue will draw together papers that address all aspects of chromatin organization and dynamics in the male germ line, in humans, and in model organisms. In particular, we will invite authors to discuss novel methods for studying germline chromatin structure, the interplay between chromatin structure and susceptibility to DNA damage and mutation, chromatin modifications associated with epigenetic inheritance in the early embryo, and the impact this work has for understanding natural fertility and improving assisted reproduction techniques.
Titolo autorizzato: Male Germline Chromatin  Visualizza cluster
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910557561103321
Lo trovi qui: Univ. Federico II
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