00929cam0 22002771 450 SOBE0004507720210623085011.020141020d1982 |||||ita|0103 baporPTEstudos sobre o seculo 16.Americo da Costa Ramalho2. ed. aumentadaLisboaImprensa nacional-Casa da moeda1982XII, 416 p.ill.24 cmTemas Portugueses001LAEC000157882001 *Temas PortuguesesRamalho, Americo : da CostaSOBA00010464070551415ITUNISOB20210623RICAUNISOBUNISOB86983126SOBE00045077M 102 Monografia moderna SBNM869000006SI83126acquistocatenacciUNISOBUNISOB20141020134950.020210623085000.0AlfanoEstudos sobre o seculo 16969860UNISOB03519nam 2200949z- 450 991055756110332120210501(CKB)5400000000044016(oapen)https://directory.doabooks.org/handle/20.500.12854/69166(oapen)doab69166(EXLCZ)99540000000004401620202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierMale Germline ChromatinBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 online resource (144 p.)3-03936-854-0 3-03936-855-9 Spermatogenesis requires radical restructuring of germline chromatin at multiple stages, involving coordinated waves of DNA methylation/demethylation, histone modification, and the replacement and removal that occurs before, during, and after meiosis. This Special Issue will draw together papers that address all aspects of chromatin organization and dynamics in the male germ line, in humans, and in model organisms. In particular, we will invite authors to discuss novel methods for studying germline chromatin structure, the interplay between chromatin structure and susceptibility to DNA damage and mutation, chromatin modifications associated with epigenetic inheritance in the early embryo, and the impact this work has for understanding natural fertility and improving assisted reproduction techniques.Biology, life sciencesbicsscResearch and information: generalbicsscassisted reproductioncentromereschromatinchromatin remodelingchromosome associationschromosome organizationchromosome paintingchromosome territorieschromosome translocationchromosomesDNA double-strand breaksDNA fragmentationDNA oxidationepigenetic inheritancegenetic instabilityhistone retentionimplantationin vitro fertilisationinfertilitymale germ cellsmale infertilitymeiotic prophasemiscarriagemorphometricsmousemouse sperm chromatinMus m. domesticusmutationsNORnuclear organisationnuclear organizationnuclear-3D-parametersnucleolioxidative stressreactive oxygen speciesreproductive agingRobertsonian chromosomesSLYspermsperm DNA damagespermatocytesspermatogenesisspermatozoaspermiogenesistelomerestestisY chromosomeBiology, life sciencesResearch and information: generalGriffin Darrenedt1318491Ellis PeteredtGriffin DarrenothEllis PeterothBOOK9910557561103321Male Germline Chromatin3033323UNINA