03498nam 2200937z- 450 991055756110332120231214133119.0(CKB)5400000000044016(oapen)https://directory.doabooks.org/handle/20.500.12854/69166(EXLCZ)99540000000004401620202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierMale Germline ChromatinBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 electronic resource (144 p.)3-03936-854-0 3-03936-855-9 Spermatogenesis requires radical restructuring of germline chromatin at multiple stages, involving coordinated waves of DNA methylation/demethylation, histone modification, and the replacement and removal that occurs before, during, and after meiosis. This Special Issue will draw together papers that address all aspects of chromatin organization and dynamics in the male germ line, in humans, and in model organisms. In particular, we will invite authors to discuss novel methods for studying germline chromatin structure, the interplay between chromatin structure and susceptibility to DNA damage and mutation, chromatin modifications associated with epigenetic inheritance in the early embryo, and the impact this work has for understanding natural fertility and improving assisted reproduction techniques.Research & information: generalbicsscBiology, life sciencesbicsscmouse sperm chromatinchromosome organizationnuclear-3D-parametersspermiogenesischromatin remodelingDNA double-strand breaksgenetic instabilitymutationssperm DNA damageDNA fragmentationinfertilityassisted reproductionmiscarriageimplantationnuclear organizationspermmorphometricschromosome paintingnucleoliNORchromosome associationsmeiotic prophasespermatocytesMus m. domesticusRobertsonian chromosomeschromosome translocationY chromosometestisspermatogenesisSLYmouseoxidative stressreactive oxygen specieschromatinDNA oxidationmale infertilityspermatozoachromosomeschromosome territoriescentromeresmale germ cellstelomeresreproductive agingnuclear organisationepigenetic inheritancehistone retentionin vitro fertilisationResearch & information: generalBiology, life sciencesGriffin Darrenedt1318491Ellis PeteredtGriffin DarrenothEllis PeterothBOOK9910557561103321Male Germline Chromatin3033323UNINA