LEADER 03498nam 2200937z- 450 001 9910557561103321 005 20231214133119.0 035 $a(CKB)5400000000044016 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/69166 035 $a(EXLCZ)995400000000044016 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMale Germline Chromatin 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 electronic resource (144 p.) 311 $a3-03936-854-0 311 $a3-03936-855-9 330 $aSpermatogenesis requires radical restructuring of germline chromatin at multiple stages, involving coordinated waves of DNA methylation/demethylation, histone modification, and the replacement and removal that occurs before, during, and after meiosis. This Special Issue will draw together papers that address all aspects of chromatin organization and dynamics in the male germ line, in humans, and in model organisms. In particular, we will invite authors to discuss novel methods for studying germline chromatin structure, the interplay between chromatin structure and susceptibility to DNA damage and mutation, chromatin modifications associated with epigenetic inheritance in the early embryo, and the impact this work has for understanding natural fertility and improving assisted reproduction techniques. 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 610 $amouse sperm chromatin 610 $achromosome organization 610 $anuclear-3D-parameters 610 $aspermiogenesis 610 $achromatin remodeling 610 $aDNA double-strand breaks 610 $agenetic instability 610 $amutations 610 $asperm DNA damage 610 $aDNA fragmentation 610 $ainfertility 610 $aassisted reproduction 610 $amiscarriage 610 $aimplantation 610 $anuclear organization 610 $asperm 610 $amorphometrics 610 $achromosome painting 610 $anucleoli 610 $aNOR 610 $achromosome associations 610 $ameiotic prophase 610 $aspermatocytes 610 $aMus m. domesticus 610 $aRobertsonian chromosomes 610 $achromosome translocation 610 $aY chromosome 610 $atestis 610 $aspermatogenesis 610 $aSLY 610 $amouse 610 $aoxidative stress 610 $areactive oxygen species 610 $achromatin 610 $aDNA oxidation 610 $amale infertility 610 $aspermatozoa 610 $achromosomes 610 $achromosome territories 610 $acentromeres 610 $amale germ cells 610 $atelomeres 610 $areproductive aging 610 $anuclear organisation 610 $aepigenetic inheritance 610 $ahistone retention 610 $ain vitro fertilisation 615 7$aResearch & information: general 615 7$aBiology, life sciences 700 $aGriffin$b Darren$4edt$01318491 702 $aEllis$b Peter$4edt 702 $aGriffin$b Darren$4oth 702 $aEllis$b Peter$4oth 906 $aBOOK 912 $a9910557561103321 996 $aMale Germline Chromatin$93033323 997 $aUNINA