From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials

• Autore: FESSARD Valérie
• Pubblicazione: Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
• Descrizione fisica: 1 online resource (188 p.)
• Soggetto topico: Humanities; Social interaction
• Soggetto non controllato: 3D culture; advanced in vitro model; AgNP; Allium cepa; aluminum; antioxidant activity; apoptosis; BEAS-2B cells; CeO2NP; comet assay; cytotoxic; cytotoxicity; DNA damage; DNA methylation; epigenetics; FPG enzyme; genotoxic; genotoxicity; graphene oxide; gut; hepatotoxicity; HepG2; high throughput screening; Hprt; Hs27 human fibroblasts; human amniotic cells; in vitro genotoxicity; in vitro testing; lincomycin; liver; liver spheroids; metal oxides; metal/coating agent ratio; micronuclei formation; micronucleus; micronucleus assay; multi-walled carbon nanotubes (MWCNT); n/a; nanomaterial; nanoparticles; nanoplastics; nanotoxicology; nongenotoxic silver nanoparticles; oral route; oxidative stress; polystyrene nanoparticles; reduced graphene oxide; safer-by-design; silver ions; SiO2NP; TiO2NP; titanium dioxide nanoparticles; tritiated particles; tungsten; V79 cells; ZnONP
• Persona (resp. second.): NesslanyFabrice; FESSARDValérie
• Sommario/riassunto: This Special Issue presents studies on the genotoxicity of nanomaterials. Although nanomaterials provide multiple benefits in a wide range of applications, challenges remain in addressing strong concerns about their risks to the environment and human health. As a result of inconsistencies among published results and diverging conclusions, the understanding of nanomaterial exposure and toxicity remains unclear. Determining whether these materials cause DNA damage-the first step in carcinogenesis-must be a priority in testing. In this book, readers will find recent publications on the genotoxic response to a broad range of nanomaterials, the impact of physico-chemical characteristics, safe-by-design and new developed tools.
• Titolo autorizzato: From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910557414003321
• Lo trovi qui: Univ. Federico II