P38 Signaling Pathway
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| Autore: |
Cuenda Ana
|
| Titolo: |
P38 Signaling Pathway
|
| Pubblicazione: | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica: | 1 online resource (194 p.) |
| Soggetto topico: | Research and information: general |
| Soggetto non controllato: | alveolar epithelial type II cells |
| Alzheimer's | |
| Alzheimer's disease | |
| amyloid-β | |
| anxiety | |
| arginine methylation | |
| arrhythmia | |
| bleomycin-induced pulmonary fibrosis | |
| cancer | |
| cocaine | |
| conditioned place preference | |
| depression | |
| endosome | |
| energy metabolism | |
| erythroid differentiation | |
| exercise | |
| hippocampus | |
| hypoxia | |
| idiopathic pulmonary fibrosis | |
| inflammation | |
| k opioid receptors | |
| Kv4.2 | |
| Lewy Bodies | |
| MAPK | |
| MAPK11 | |
| metabolism | |
| MKK3 | |
| n/a | |
| neuroinflammation | |
| neuronal firing and excitability | |
| nuclear translocation | |
| nucleus accumbens | |
| p38 | |
| p38 MAPK | |
| p38 mitogen-activated protein kinase | |
| p38-MAPK α inhibitor | |
| p38MAPK | |
| p38α | |
| p38β | |
| phosphorylation, PRMT1 | |
| physiology | |
| Rab5 | |
| reward | |
| RNA sequencing | |
| seizure | |
| signal transduction | |
| signaling | |
| skeletal muscle | |
| social interaction | |
| stress | |
| synaptic plasticity | |
| tau | |
| Tau | |
| temporal lobe epilepsy | |
| type 2 diabetes | |
| α-synuclein | |
| β-amyloid | |
| β-like importins | |
| Persona (resp. second.): | Sanz EzquerroJuan José |
| CuendaAna | |
| Sommario/riassunto: | p38 Mitogen activated protein kinases (p38MAPK) are a group of evolutionary conserved protein kinases which are central for cell adaptation to environmental changes as well as for immune response, inflammation, tissue regeneration and tumour formation. The interest in this group of protein kinases has grown continually since their discovery. Recent studies using new genetic and pharmacological tools are providing helpful information on the function of these stress-activated protein kinases and show that they have an acute impact on the development of prevalent diseases related to inflammation, diabetes, neurodegeneration, and cancer. In this Special Issue we present novel advances and review the knowledge on the identification of p38MAPK substrates, functions, and regulation; mechanisms underlying the role of p38MAPK in malignant transformation and other pathologies; and therapeutic opportunities associated with regulation of p38MAPK activity. |
| Titolo autorizzato: | P38 Signaling Pathway |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910557702003321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |