LEADER 03800nam  2201033z- 450 
001 9910557702003321
005 20231214133404.0
035   $a(CKB)5400000000046260
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/76473
035   $a(EXLCZ)995400000000046260
100   $a20202201d2021      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aP38 Signaling Pathway
210   $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2021
215   $a1 electronic resource (194 p.)
311   $a3-0365-0858-9 
311   $a3-0365-0859-7 
330   $ap38 Mitogen activated protein kinases (p38MAPK) are a group of evolutionary conserved protein kinases which are central for cell adaptation to environmental changes as well as for immune response, inflammation, tissue regeneration and tumour formation. The interest in this group of protein kinases has grown continually since their discovery. Recent studies using new genetic and pharmacological tools are providing helpful information on the function of these stress-activated protein kinases and show that they have an acute impact on the development of prevalent diseases related to inflammation, diabetes, neurodegeneration, and cancer. In this Special Issue we present novel advances and review the knowledge on the identification of p38MAPK substrates, functions, and regulation; mechanisms underlying the role of p38MAPK in malignant transformation and other pathologies; and therapeutic opportunities associated with regulation of p38MAPK activity.
606   $aResearch & information: general$2bicssc
610   $aarginine methylation
610   $aerythroid differentiation
610   $aMKK3
610   $aphosphorylation, PRMT1
610   $ap38 MAPK
610   $acocaine
610   $aconditioned place preference
610   $areward
610   $astress
610   $aanxiety
610   $adepression
610   $anucleus accumbens
610   $asocial interaction
610   $ak opioid receptors
610   $ap38?
610   $aRab5
610   $aendosome
610   $aAlzheimer's
610   $aLewy Bodies
610   $aamyloid-?
610   $atau
610   $a?-synuclein
610   $ap38-MAPK ? inhibitor
610   $aAlzheimer's disease
610   $asynaptic plasticity
610   $aneuroinflammation
610   $a?-amyloid
610   $aTau
610   $aKv4.2
610   $aseizure
610   $atemporal lobe epilepsy
610   $ahippocampus
610   $aneuronal firing and excitability
610   $ap38MAPK
610   $anuclear translocation
610   $a?-like importins
610   $ainflammation
610   $acancer
610   $askeletal muscle
610   $aenergy metabolism
610   $asignal transduction
610   $aexercise
610   $atype 2 diabetes
610   $ap38 mitogen-activated protein kinase
610   $ableomycin-induced pulmonary fibrosis
610   $aidiopathic pulmonary fibrosis
610   $aRNA sequencing
610   $aalveolar epithelial type II cells
610   $aMAPK
610   $ap38
610   $aphysiology
610   $ametabolism
610   $asignaling
610   $ahypoxia
610   $aarrhythmia
610   $aMAPK11
610   $ap38?
615  7$aResearch & information: general
700   $aCuenda$b Ana$4edt$01327925
702   $aSanz Ezquerro$b Juan Jose?$4edt
702   $aCuenda$b Ana$4oth
702   $aSanz Ezquerro$b Juan Jose?$4oth
906   $aBOOK
912   $a9910557702003321
996   $aP38 Signaling Pathway$93038283
997   $aUNINA