Palladium and Nickel Catalyzed Transformations Forming Functionalized Heterocycles / / by Hyung Yoon
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| Autore: |
Yoon Hyung
|
| Titolo: |
Palladium and Nickel Catalyzed Transformations Forming Functionalized Heterocycles / / by Hyung Yoon
|
| Pubblicazione: | Springer International Publishing, 2020 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | |
| Edizione: | 1st ed. 2020. |
| Descrizione fisica: | 1 online resource (XXIX, 212 p. 552 illus., 35 illus. in color.) |
| Disciplina: | 541.395 |
| Soggetto topico: | Catalysis |
| Chemistry, Inorganic | |
| Chemistry, Organic | |
| Organometallic chemistry | |
| Chemistry, Physical and theoretical | |
| Inorganic Chemistry | |
| Organic Chemistry | |
| Organometallic Chemistry | |
| Physical Chemistry | |
| Nota di contenuto: | Chapter 1. Carbohalogenation Catalyzed by Palladium and Nickel -- Chapter 2. Diastereoselective Pd-Catalyzed Aryl Cyanation and Aryl Borylation -- Chapter 3. Pd-Catalyzed Spirocyclization via C–H Activation and Benzyne/Alkyne Insertion. |
| Sommario/riassunto: | This book presents Pd- and Ni-catalyzed transformations generating functionalized heterocycles. Transition metal catalysis is at the forefront of synthetic organic chemistry since it offers new and powerful methods to forge carbon–carbon bonds in high atom- and step-economy. In Chapter 1, the author describes a Pd- and Ni-catalyzed cycloisomerization of aryl iodides to alkyl iodides, known as carboiodination. In the context of the Pd-catalyzed variant, the chapter explores the production of enantioenriched carboxamides through diastereoselective Pd-catalyzed carboiodination. It then discusses Ni-catalyzed reactions to generate oxindoles and an enantioselective variant employing a dual ligand system. Chapter 2 introduces readers to a Pd-catalyzed diastereoselective anion-capture cascade. It also examines diastereoselective Pd-catalyzed aryl cyanation to synthesize alkyl nitriles, a method that generates high yields of borylated chromans as a single diastereomer, and highlights its synthetic utility. Lastly, Chapter 3 presents a Pd-catalyzed domino process harnessing carbopalladation, C–H activation and π-system insertion (benzynes and alkynes) to generate spirocycles. It also describes the mechanistic studies performed on these reactions. |
| Titolo autorizzato: | Palladium and Nickel Catalyzed Transformations Forming Functionalized Heterocycles |
| ISBN: | 3-030-54077-4 |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910863189903321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |
Serie:
Springer Theses, Recognizing Outstanding Ph.D. Research, . 2190-5053