04154nam 22006855 450 991086318990332120250610110429.03-030-54077-410.1007/978-3-030-54077-7(CKB)4100000011413891(DE-He213)978-3-030-54077-7(MiAaPQ)EBC6335302(PPN)250221519(MiAaPQ)EBC29092730(EXLCZ)99410000001141389120200902d2020 u| 0engurnn|008mamaatxtrdacontentcrdamediacrrdacarrierPalladium and Nickel Catalyzed Transformations Forming Functionalized Heterocycles /by Hyung Yoon1st ed. 2020.Springer International Publishing2020Cham :Springer International Publishing :Imprint: Springer,2020.1 online resource (XXIX, 212 p. 552 illus., 35 illus. in color.) Springer Theses, Recognizing Outstanding Ph.D. Research,2190-50533-030-54076-6 Chapter 1. Carbohalogenation Catalyzed by Palladium and Nickel -- Chapter 2. Diastereoselective Pd-Catalyzed Aryl Cyanation and Aryl Borylation -- Chapter 3. Pd-Catalyzed Spirocyclization via C–H Activation and Benzyne/Alkyne Insertion.This book presents Pd- and Ni-catalyzed transformations generating functionalized heterocycles. Transition metal catalysis is at the forefront of synthetic organic chemistry since it offers new and powerful methods to forge carbon–carbon bonds in high atom- and step-economy. In Chapter 1, the author describes a Pd- and Ni-catalyzed cycloisomerization of aryl iodides to alkyl iodides, known as carboiodination. In the context of the Pd-catalyzed variant, the chapter explores the production of enantioenriched carboxamides through diastereoselective Pd-catalyzed carboiodination. It then discusses Ni-catalyzed reactions to generate oxindoles and an enantioselective variant employing a dual ligand system. Chapter 2 introduces readers to a Pd-catalyzed diastereoselective anion-capture cascade. It also examines diastereoselective Pd-catalyzed aryl cyanation to synthesize alkyl nitriles, a method that generates high yields of borylated chromans as a single diastereomer, and highlights its synthetic utility. Lastly, Chapter 3 presents a Pd-catalyzed domino process harnessing carbopalladation, C–H activation and π-system insertion (benzynes and alkynes) to generate spirocycles. It also describes the mechanistic studies performed on these reactions.Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053CatalysisChemistry, InorganicChemistry, OrganicOrganometallic chemistryChemistry, Physical and theoreticalCatalysishttps://scigraph.springernature.com/ontologies/product-market-codes/C29000Inorganic Chemistryhttps://scigraph.springernature.com/ontologies/product-market-codes/C16008Organic Chemistryhttps://scigraph.springernature.com/ontologies/product-market-codes/C19007Organometallic Chemistryhttps://scigraph.springernature.com/ontologies/product-market-codes/C19020Physical Chemistryhttps://scigraph.springernature.com/ontologies/product-market-codes/C21001Catalysis.Chemistry, Inorganic.Chemistry, Organic.Organometallic chemistry.Chemistry, Physical and theoretical.Catalysis.Inorganic Chemistry.Organic Chemistry.Organometallic Chemistry.Physical Chemistry.541.395Yoon Hyungauthttp://id.loc.gov/vocabulary/relators/aut1065403MiAaPQMiAaPQMiAaPQBOOK9910863189903321Palladium and Nickel Catalyzed Transformations Forming Functionalized Heterocycles2545056UNINA