Thermodynamics of pharmaceutical systems [[electronic resource] ] : an introduction to theory and applications / / Kenneth A. Connors, Sandro Mecozzi

• Autore: Connors Kenneth A (Kenneth Antonio), <1932->
• Pubblicazione: Hoboken, NJ, : John Wiley & Sons, c2010
• Edizione: 2nd ed.
• Descrizione fisica: 1 online resource (379 p.)
• Disciplina: 615.19; 615/.19
• Soggetto topico: Pharmaceutical chemistry; Thermodynamics
• Soggetto genere / forma: Electronic books.
• Altri autori: MecozziSandro
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: THERMODYNAMICS OF PHARMACEUTICAL SYSTEMS; CONTENTS; PREFACE; PREFACE TO THE FIRST EDITION; 0. Review of Mathematics; 0.1. Introduction; 0.2. Dimensions and Units; 0.3. Logarithms and Exponents; 0.4. Algebraic and Graphical Analysis; 0.5. Dealing with Change; 0.6. Statistical Treatment of Data; Problems; I BASIC THERMODYNAMICS; 1. Energy and the First Law of Thermodynamics; 1.1. Fundamental Concepts; 1.2. The First Law of Thermodynamics; 1.3. The Enthalpy; Problems; 2. The Entropy Concept; 2.1. The Entropy Defined; 2.2. The Second Law of Thermodynamics; 2.3. Applications of the Entropy Concept ; Problems3. The Free Energy; 3.1. Properties of the Free Energy; 3.2. The Chemical Potential; Problems; 4. Equilibrium; 4.1. Conditions for Equilibrium; 4.2. Physical Processes; 4.3. Chemical Equilibrium; Problems; II THERMODYNAMICS OF PHYSICAL PROCESSES; 5. Introduction to Physical Processes; 5.1. Scope; 5.2. Concentration Scales; 5.3. Standard States; Problems; 6. Phase Transformations; 6.1. Pure Substances; 6.2. Multicomponent Systems; Problems; 7. Solutions of Nonelectrolytes; 7.1. Ideal Solutions; 7.2. Nonideal Solutions; 7.3. Partitioning Between Liquid Phases; Problems ; 8. Solutions of Electrolytes8.1. Coulombic Interaction and Ionic Dissociation; 8.2. Mean Ionic Activity and Activity Coefficient; 8.3. The Debye-Hückel Theory; Problems; 9. Colligative Properties; 9.1. Boiling Point Elevation; 9.2. Freezing Point Depression; 9.3. Osmotic Pressure; 9.4. Isotonicity Calculations; Problems; 10. Solubility; 10.1. Solubility as an Equilibrium Constant; 10.2. The Ideal Solubility; 10.3. Temperature Dependence of the Solubility; 10.4. Solubility of Slightly Soluble Salts; 10.5. Solubilities of Nonelectrolytes: Further Issues; Problems; 11. Surfaces and Interfaces ; 11.1. Thermodynamic Properties11.2. Adsorption; Problems; III THERMODYNAMICS OF CHEMICAL PROCESSES; 12. Acid-Base Equilibria; 12.1. Acid-Base Theory; 12.2. pH Dependence of Acid-Base Equilibria; 12.3. Calculation of Solution pH; 12.4. Acid-Base Titrations; 12.5. Aqueous Solubility of Weak Acids and Bases; 12.6. Nonaqueous Acid-Base Behavior; 12.7. Acid-Base Structure and Strength; Problems; 13. Electrical Work; 13.1. Introduction; 13.2. Oxidation-Reduction Reactions; 13.3. Electrochemical Cells; 13.4. pH Measurement; 13.5. Ion-Selective Membrane Electrodes; Problems ; 14. Noncovalent Binding Equilibria14.1. Introduction; 14.2. The Noncovalent Interactions; 14.3. Binding Models; 14.4. Measurement of Binding Constants; 14.5. Applications; Problems; APPENDIXES; Appendix A Physical Constants; Appendix B Kinetic Theory of Gases; Appendix C Extrathermodynamic Relationships; ANSWERS TO PROBLEMS; BIBLIOGRAPHY; INDEX
• Sommario/riassunto: Designed for pharmacy students Now updated for its Second Edition, Thermodynamics of Pharmaceutical Systems provides pharmacy students with a much-needed introduction to the mathematical intricacies of thermodynamics in relation to practical laboratory applications. Designed to meet the needs of the contemporary curriculum in pharmacy schools, the text makes these connections clear, emphasizing specific applications to pharmaceutical systems including dosage forms and newer drug delivery systems. Students and practitioners involved in drug discovery, drug delivery, and drug a
• Titolo autorizzato: Thermodynamics of pharmaceutical systems
• ISBN: 1-282-49085-0; 9786612490859; 0-470-56752-X; 0-470-56751-1
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910457240503321
• Lo trovi qui: Univ. Federico II