Molecular and cellular toxicology : an introduction / / Dr. Lesley A. Stanley

• Autore: Stanley Lesley
• Pubblicazione: Chichester, England : , : Wiley Blackwell, , 2014; ©2014
• Descrizione fisica: 1 online resource (435 p.)
• Disciplina: 615.9/07
• Soggetto topico: Toxicity Tests; Molecular biology; Xenobiotics - toxicity
• Soggetto genere / forma: Electronic books.
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references at the end of each chapters and index.
• Nota di contenuto: Background to molecular and cellular toxicology -- Individual susceptibility to toxic chemicals -- Omics techniques -- In vitro methods for predicting in vivo toxicity -- In vitro methods for absorption, distribution, metabolism and excretion -- In silico methods and structure-activity relationships -- Transgenic animal models for ADME and systemic toxicity -- Genotoxicity and its measurement -- Oncogenes and the identification of human carcinogens -- Emerging techniques.
• Sommario/riassunto: Toxicology is the study of the adverse effects of chemical, physical, or biological agents on people, animals, and the environment. Toxicologists are trained to investigate, interpret, and communicate the nature of those effects. Over the last ten years the subject of toxicology has changed dramatically, moving from a discipline which was once firmly wedded to traditional methods to one which is keen to embrace the innovative techniques emerging from the developing fields of cell culture and molecular biology. There is an acute need for this to be reflected in a paradigm shift which
• Titolo autorizzato: Molecular and cellular toxicology
• ISBN: 1-119-95207-7; 1-118-52607-4; 1-118-52601-5; 1-118-52606-6
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910453772803321
• Lo trovi qui: Univ. Federico II