Inflammation and Lung Cancer / / edited by Steven M. Dubinett

• Pubblicazione: New York, NY : , : Springer New York : , : Imprint : Springer, , 2015
• Edizione: 1st ed. 2015.
• Descrizione fisica: 1 online resource (215 p.)
• Disciplina: 610; 614.5999; 616.07; 616.079; 616.9041
• Soggetto topico: Cancer - Research; Pathology; Medical microbiology; Immunology; Cancer Research; Medical Microbiology
• Persona (resp. second.): DubinettSteven M
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references at the end of each chapters and index.
• Nota di contenuto: Inflammation and Lung Cancer: The relationship to COPD -- Inflammation and Lung Cancer: The role of EMT -- Inflammation and Lung Cancer: Molecular pathology -- Inflammation and Lung Cancer: Prevention -- Inflammation and Lung Cancer: The Link to Angiogenesis -- Inflammation and Lung Cancer: Eicosanoids -- Inflammation and Lung Cancer: Addressing Inflammation with Immunotherapy.
• Sommario/riassunto: This volume presents aspects of the inflammatory tumor microenvironment (TME) and its many roles in tumor progression and metastasis, including creation of a hypoxic environment, increased angiogenesis and invasion, changes in expression of microRNAs (miRNAs), and an increase in a stem cell phenotype. The volume also covers the mechanisms of inflammatory mediators. Chronic overexpression of inflammatory mediators in the TME, as seen in smokers and patients with non-small cell lung cancer (NSCLC), can also lead to increased tumor initiation, progression, invasion, and metastasis. The volume will provide a comprehensive perspective of the latest findings and summaries of progress made regarding inflammation and its connection to lung cancer.
• Titolo autorizzato: Inflammation and Lung Cancer
• ISBN: 1-4939-2724-8
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910298268203321
• Lo trovi qui: Univ. Federico II