LEADER 03437nam 22006975 450 001 9910298268203321 005 20200703172544.0 010 $a1-4939-2724-8 024 7 $a10.1007/978-1-4939-2724-1 035 $a(CKB)3710000000436712 035 $a(EBL)2094766 035 $a(SSID)ssj0001524947 035 $a(PQKBManifestationID)11979183 035 $a(PQKBTitleCode)TC0001524947 035 $a(PQKBWorkID)11485422 035 $a(PQKB)11373386 035 $a(DE-He213)978-1-4939-2724-1 035 $a(MiAaPQ)EBC2094766 035 $a(PPN)186395876 035 $a(EXLCZ)993710000000436712 100 $a20150624d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aInflammation and Lung Cancer /$fedited by Steven M. Dubinett 205 $a1st ed. 2015. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2015. 215 $a1 online resource (215 p.) 300 $aDescription based upon print version of record. 311 $a1-4939-2723-X 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aInflammation and Lung Cancer: The relationship to COPD -- Inflammation and Lung Cancer: The role of EMT -- Inflammation and Lung Cancer: Molecular pathology -- Inflammation and Lung Cancer: Prevention -- Inflammation and Lung Cancer: The Link to Angiogenesis -- Inflammation and Lung Cancer: Eicosanoids -- Inflammation and Lung Cancer: Addressing Inflammation with Immunotherapy. 330 $aThis volume  presents aspects of the inflammatory tumor microenvironment (TME) and its many roles in tumor progression and metastasis, including creation of a hypoxic environment, increased angiogenesis and invasion, changes in expression of microRNAs (miRNAs), and an increase in a stem cell phenotype. The volume also covers the mechanisms of inflammatory mediators. Chronic overexpression of inflammatory mediators in the TME, as seen in smokers and patients with non-small cell lung cancer (NSCLC), can also lead to increased tumor initiation, progression, invasion, and metastasis. The volume will provide a comprehensive perspective of the latest findings and summaries of progress made regarding inflammation and its connection to lung cancer. 606 $aCancer$xResearch 606 $aPathology 606 $aMedical microbiology 606 $aImmunology 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 606 $aPathology$3https://scigraph.springernature.com/ontologies/product-market-codes/H4800X 606 $aMedical Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B16003 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 615 0$aCancer$xResearch. 615 0$aPathology. 615 0$aMedical microbiology. 615 0$aImmunology. 615 14$aCancer Research. 615 24$aPathology. 615 24$aMedical Microbiology. 615 24$aImmunology. 676 $a610 676 $a614.5999 676 $a616.07 676 $a616.079 676 $a616.9041 702 $aDubinett$b Steven M$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910298268203321 996 $aInflammation and Lung Cancer$92539264 997 $aUNINA