Hyaluronic acid : preparation, properties, application in biology and medicine / / Mikhail A. Selyanin, Petr Ya. Boykov and Vladimir N. Khabarov ; translated from the Russian version by scientific editor Felix Polyak

• Autore: Selyanin M. A (Michael A.)
• Pubblicazione: Chichester, England : , : Wiley, , 2015; ©2015
• Descrizione fisica: 1 online resource (215 p.)
• Disciplina: 612.015782
• Soggetto topico: Hyaluronic acid; Organic acids
• Persona (resp. second.): BoykovP. Ya; KhabarovV. N (Vladimir N.); PolyakFelix
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references at the end of each chapters and index.
• Nota di contenuto: Title Page; Copyright Page; Contents; Foreword; Introduction; Chapter 1 The History of Hyaluronic Acid Discovery, Foundational Research and Initial Use; 1.1 Discovery; 1.2 Foundational Research; 1.3 Initial Medical Applications; 1.4 Sources of Hyaluronan; 1.5 Current Medical Study and Use; 1.6 Impact and Future Directions; References; Chapter 2 The Biological Role of Hyaluronic Acid; 2.1 Hyaluronic Acid Phylogenesis; 2.1.1 Polysaccharide Structure and the Problems of Phylogenesis; 2.1.2 Physico-Chemical and Functional Differences of Polysaccharides ; 2.1.3 Biochemical Features of Hyaluronic Acid and Other Glycosaminoglycans2.2 Functions of Hyaluronan in Human Ontogenesis; 2.2.1 Role of Hyaluronic Acid in Fertilization; 2.2.2 Hyaluronan and Other Glucosaminoglycans in Cell Division, Migration and Differentiation; 2.2.3 Hyaluronic Acid and Sulfated Glycosaminoglycans in Maintaining a Differentiated Status of Cells; 2.2.4 Hyaluronan and Induction of Cellular Cycles for Differentiated Cells; 2.2.5 The Source of Hyaluronic Acid's Functional Properties and the Dynamics of its Synthesis and Degradation ; 2.2.6 The Rules of Biopolymer Functional Cleavage2.3 Hyaluronan Signalling Systems; 2.4 Hyaluronan Functions in the Extracellular Matrix; 2.4.1 Extracellular Space; 2.4.2 Composition and Functioning of the Extracellular Matrix; 2.4.3 The Role of Hyaluronan in Transportation of Substances through the Extracellular Matrix: Diffusion, Osmosis, Electro-Osmosis and Vesicular Transportation; 2.4.4 Hyaluronan in the Extracellular Matrix of Different Connective Tissues; References; Chapter 3 Methods of Hyaluronic Acid Production; 3.1 Hyaluronan Sources and Extraction ; 3.1.1 Hyaluronan Production from Animal Sources: General Methods3.1.2 Hyaluronan Purification; 3.1.3 The Chemical Production of Hyaluronan from Chicken Combs; 3.1.4 HA Production for Ophthalmology; 3.2 Bacterial Methods of Hyaluronic Acid Production; 3.3 Hyaluronan Destruction during Production, Storage and Sterilization; 3.4 Enzymatic Destruction of Hyaluronan; 3.4.1 Hyaluronidase Classification; 3.4.2 Properties and Functions of Hyaluronidases; 3.5 Non-Enzymatic Destruction of Hyaluronan; 3.5.1 Acid-Base Hydrolysis of Hyaluronan; 3.5.2 Oxidation-Reduction Depolymerization of Hyaluronan ; 3.6 Quality of Hyaluronan Commercial Products of Animal and Bacterial OriginReferences; Chapter 4 Molecular and Supramolecular Structure of Hyaluronic Acid; 4.1 Primary Structure of Hyaluronic Acid; 4.2 Structure of Hyaluronan in Solution; 4.3 Rheological Properties of Hyaluronic Acid; References; Chapter 5 Chemical Modifications, Solid Phase, Radio-Chemical and Enzymatic Transformations of Hyaluronic Acid; 5.1 Main Characteristics of Cross-Linked Hydrogels; 5.2 Methods of Hyaluronic Acid Cross-Linking; 5.2.1 Cross-Linking with Carbodiimides; 5.2.2 Cross-Linking with Aldehydes ; 5.2.3 Cross-Linking with Divinylsulfone
• Sommario/riassunto: Hyaluronic acid is an essential part of connective, epithelialand neural tissues, and contributes to cell proliferation andmigration. It is used as a stimulating agent for collagen synthesisand is a common ingredient in skin-care products, a multi-billiondollar industry, as it is believed to be a key factor in fightingthe aging process. Hyaluronic Acid: Production, Properties, Application inBiology and Medicine consists of six chapters discussing thevarious issues of hyaluronic acid research. In Chapter 1, ahistorical analysis recounts the discovery and milestones of theresearch leading to t
• Titolo autorizzato: Hyaluronic acid
• ISBN: 1-118-69595-X; 1-118-69593-3; 1-118-69592-5
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910132397603321
• Lo trovi qui: Univ. Federico II