Macropinocytosis : Functions and Mechanisms / / edited by Cosimo Commisso
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| Titolo: |
Macropinocytosis : Functions and Mechanisms / / edited by Cosimo Commisso
|
| Pubblicazione: | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 |
| Edizione: | 1st ed. 2022. |
| Descrizione fisica: | 1 online resource (227 pages) |
| Disciplina: | 571.6 |
| Soggetto topico: | Cytology |
| Biophysics | |
| Cell interaction | |
| Biological transport | |
| Cell membranes | |
| Medicine - Research | |
| Biology - Research | |
| Cell Biology | |
| Mechanobiological Cell Signaling | |
| Membrane Trafficking | |
| Biomedical Research | |
| Persona (resp. second.): | CommissoCosimo |
| Note generali: | Includes index. |
| Nota di contenuto: | Part 1: Functions of Macropinocytosis -- Chapter 1: Functional Diversity of Macropinocytosis -- Chapter 2: Macropinocytosis and Cancer: From Tumor Stress to Signaling Pathways -- Chapter 3: The amoebal model for micropinocytosis -- Chapter 4: Extracellular ATP and macropinocytosis -- Chapter 5: Macropinocytosis and Cell Migration: Don't drink an drive -- Chapter 6: Macropinocytosis in phagocyte function and immunity -- Part 2: Signaling Mechanisms Driving Macropinocytosis -- Chapter 7: Roles of 3' Phosphoinositides in Macropinocytosis -- Chapter 8: Signaling pathways that regulate macropinocytosis in mammalian cells -- Chapter 9: Wnt, GSK3 and Macropinocytosis -- Chapter 10: Kras addiction promotes cancer cell adapation in harsh microenvironment through micropinocytosis -- Chapter 11: Kras-independent macropinocytosis in pancreatic cancer. |
| Sommario/riassunto: | This book presents the functions and mechanisms of macropinocytosis, an actin-driven endocytic uptake process. Key points, including the evolutionary origins of macropinocytosis and major signaling pathways that regulate this uptake mechanism, are highlighted. A wide-array of functions of macropinocytosis are described, including cellular metabolism, cell death, cell migration and antigen presentation. Macropinocytosis has recently been recognized as a critical pathway in disease pathology and treatment. Therefore, a broad overview of macropinocytosis will benefit clinicians, as well as translational and basic research scientists. Moreover, as one of the main clathrin-independent endocytic routes, compiling all the critical information about macropinocytosis in one collection, this book will also be helpful to educators and their students. |
| Titolo autorizzato: | Macropinocytosis |
| ISBN: | 9783030940041 |
| 9783030940034 | |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910559393403321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |
Serie:
Subcellular Biochemistry, . 2542-8810 ; ; 98