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Flipons : The Discovery of Z-DNA and Soft-Wired Genomes



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Autore: Herbert Alan Visualizza persona
Titolo: Flipons : The Discovery of Z-DNA and Soft-Wired Genomes Visualizza cluster
Pubblicazione: Milton : , : Taylor & Francis Group, , 2024
©2024
Edizione: 1st ed.
Descrizione fisica: 1 online resource (287 pages)
Disciplina: 572.86
Soggetto topico: Genomics
Gene mapping
Genomes
Nota di contenuto: Cover -- Half Title -- Title Page -- Copyright Page -- Dedication -- Table of Contents -- Preface -- Acknowledgements -- About the Author -- Part I -- Chapter 1 The Dawn -- What Is DNA? -- In the Beginning -- Chapter 2 Even Smart People Are Sometimes Wrong -- The First Sighting of Left-handed Z-DNA -- Chapter 3 Coming to America -- Chapter 4 From One Unknown to Another -- Chapter 5 Failing Successfully Everywhere Else: The In-between Years -- The Framingham Years -- The Merck Experience -- Chapter 6 How Do You Know It's You? The Answer Lies in Your Z-RNA -- Chapter 7 Can Left-handed Z-DNA and Z-RNA Kill You? -- Chapter 8 Does Z-DNA Regulate Transcription? -- Chapter 9 Luck and the Business of Science -- Part II -- Chapter 10 What about Other Types of Flipons? -- Other Types of Flipons -- G-flipons -- T-flipons -- L-flipons -- Chapter 11 Is Your Genome Soft-wired? -- Shaping DNA with RNA -- Chapter 12 How Do You Assemble a Soft-wired Genome? -- Peptide Patches -- Peptide Patches and Evolution -- Chapter 13 How Do You Program a Soft-wired Genome? -- Chapter 14 Is Life Intransitive? -- Chapter 15 Are RNA Therapeutics the Wave of the Future? -- Epilogue: Why Have a Career in Science? -- References -- Index.
Sommario/riassunto: Alan Herbert has played a leading part in discovering the biological roles for a high-energy form of DNA twisted to the left rather than to the right. Both Z-DNA and the Z-RNA sensing proteins are critical for protecting hosts against both viruses and cancers.
Titolo autorizzato: Flipons  Visualizza cluster
ISBN: 9781040024959
1040024955
9781040025000
1040025005
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910842263503321
Lo trovi qui: Univ. Federico II
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