Solid state characterization of pharmaceuticals [[electronic resource] /] / editors, Richard A. Storey, Ingvar Ymén

• Pubblicazione: Chichester, U.K., : John Wiley & Sons, 2011
• Descrizione fisica: 1 online resource (528 p.)
• Disciplina: 615/.19
• Soggetto topico: Solid dosage forms; Drugs - Design; Pharmaceutical chemistry
• Altri autori: StoreyRichard A YmenIngvar
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Introduction to the solid state : physical properties and processes -- X-ray diffraction -- Spectroscopic characterisation -- Dielectric spectroscopy and thermally stimulated current spectroscopy : use in the characterisation of solid state pharmaceutical systems -- Solid state characterisation of pharmaceuticals -- Calorimetric methods : solution calorimetry -- Vapour sorption for bulk and surface analysis -- Microscopy -- Mechanical properties of pharmaceutical materials -- Particle size assessment -- Computational polymorph prediction -- Patenting of inventions relating to polymorphs -- A 'roadmap' to solid form selection.
• Sommario/riassunto: The field of solid state characterization is central to the pharmaceutical industry, as drug products are, in an overwhelming number of cases, produced as solid materials. Selection of the optimum solid form is a critical aspect of the development of pharmaceutical compounds, due to their ability to exist in more than one form or crystal structure (polymorphism). These polymorphs exhibit different physical properties which can affect their biopharmaceutical properties. This book provides an up-to-date review of the current techniques used to characterize pharmaceutical solids. Ensuring balan
• Titolo autorizzato: Solid state characterization of pharmaceuticals
• ISBN: 1-283-20346-4; 9786613203465; 1-119-97017-2; 0-470-65935-1; 0-470-65679-4
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910130870803321
• Lo trovi qui: Univ. Federico II