LEADER 03095nam 2200637 a 450 001 9910130870803321 005 20200520144314.0 010 $a1-283-20346-4 010 $a9786613203465 010 $a1-119-97017-2 010 $a0-470-65935-1 010 $a0-470-65679-4 035 $a(CKB)3460000000000125 035 $a(EBL)711788 035 $a(OCoLC)711780324 035 $a(SSID)ssj0000541431 035 $a(PQKBManifestationID)12181599 035 $a(PQKBTitleCode)TC0000541431 035 $a(PQKBWorkID)10499052 035 $a(PQKB)10412482 035 $a(MiAaPQ)EBC711788 035 $a(Au-PeEL)EBL711788 035 $a(CaPaEBR)ebr10484890 035 $a(CaONFJC)MIL320346 035 $a(PPN)243368658 035 $a(EXLCZ)993460000000000125 100 $a20101221d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aSolid state characterization of pharmaceuticals$b[electronic resource] /$feditors, Richard A. Storey, Ingvar Yme?n 210 $aChichester, U.K. $cJohn Wiley & Sons$d2011 215 $a1 online resource (528 p.) 300 $aDescription based upon print version of record. 311 $a1-4051-3494-1 320 $aIncludes bibliographical references and index. 327 $aIntroduction to the solid state : physical properties and processes -- X-ray diffraction -- Spectroscopic characterisation -- Dielectric spectroscopy and thermally stimulated current spectroscopy : use in the characterisation of solid state pharmaceutical systems -- Solid state characterisation of pharmaceuticals -- Calorimetric methods : solution calorimetry -- Vapour sorption for bulk and surface analysis -- Microscopy -- Mechanical properties of pharmaceutical materials -- Particle size assessment -- Computational polymorph prediction -- Patenting of inventions relating to polymorphs -- A 'roadmap' to solid form selection. 330 $aThe field of solid state characterization is central to the pharmaceutical industry, as drug products are, in an overwhelming number of cases, produced as solid materials. Selection of the optimum solid form is a critical aspect of the development of pharmaceutical compounds, due to their ability to exist in more than one form or crystal structure (polymorphism). These polymorphs exhibit different physical properties which can affect their biopharmaceutical properties. This book provides an up-to-date review of the current techniques used to characterize pharmaceutical solids. Ensuring balan 606 $aSolid dosage forms 606 $aDrugs$xDesign 606 $aPharmaceutical chemistry 615 0$aSolid dosage forms. 615 0$aDrugs$xDesign. 615 0$aPharmaceutical chemistry. 676 $a615/.19 701 $aStorey$b Richard A$0109522 701 $aYmen$b Ingvar$0958660 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910130870803321 996 $aSolid state characterization of pharmaceuticals$92172256 997 $aUNINA LEADER 03765nam 22006135 450 001 9910300157403321 005 20200630072242.0 010 $a3-642-40523-1 024 7 $a10.1007/978-3-642-40523-5 035 $a(CKB)3710000000078652 035 $a(MH)013863957-4 035 $a(SSID)ssj0001049494 035 $a(PQKBManifestationID)11602091 035 $a(PQKBTitleCode)TC0001049494 035 $a(PQKBWorkID)11020042 035 $a(PQKB)10276716 035 $a(DE-He213)978-3-642-40523-5 035 $a(MiAaPQ)EBC3107081 035 $a(PPN)17611484X 035 $a(EXLCZ)993710000000078652 100 $a20131028d2014 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cn$2rdamedia 183 $anc$2rdacarrier 200 13$aAn Introduction to Markov Processes /$fby Daniel W. Stroock 205 $a2nd ed. 2014. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2014. 215 $a1 online resource (xv, 203 pages ) 225 1 $aGraduate Texts in Mathematics,$x0072-5285 ;$v230 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a3-642-40522-3 320 $aIncludes bibliographical references (page 199) and index. 327 $aPreface -- Random Walks, a Good Place to Begin -- Doeblin's Theory for Markov Chains -- Stationary Probabilities -- More about the Ergodic Theory of Markov Chains -- Markov Processes in Continuous Time -- Reversible Markov Processes -- A minimal Introduction to Measure Theory -- Notation -- References -- Index. 330 $aThis book provides a rigorous but elementary introduction to the theory of Markov Processes on a countable state space. It should be accessible to students with a solid undergraduate background in mathematics, including students from engineering, economics, physics, and biology. Topics covered are: Doeblin's theory, general ergodic properties, and continuous time processes. Applications are dispersed throughout the book. In addition, a whole chapter is devoted to reversible processes and the use of their associated Dirichlet forms to estimate the rate of convergence to equilibrium. These results are then applied to the analysis of the Metropolis (a.k.a simulated annealing) algorithm. The corrected and enlarged 2nd edition contains a new chapter in which the author develops computational methods for Markov chains on a finite state space. Most intriguing is the section with a new technique for computing stationary measures, which is applied to derivations of Wilson's algorithm and Kirchoff's formula for spanning trees in a connected graph. 410 0$aGraduate Texts in Mathematics,$x0072-5285 ;$v230 606 $aProbabilities 606 $aDynamics 606 $aErgodic theory 606 $aProbability Theory and Stochastic Processes$3https://scigraph.springernature.com/ontologies/product-market-codes/M27004 606 $aDynamical Systems and Ergodic Theory$3https://scigraph.springernature.com/ontologies/product-market-codes/M1204X 615 0$aProbabilities. 615 0$aDynamics. 615 0$aErgodic theory. 615 14$aProbability Theory and Stochastic Processes. 615 24$aDynamical Systems and Ergodic Theory. 676 $a519.2 700 $aStroock$b Daniel W$4aut$4http://id.loc.gov/vocabulary/relators/aut$042628 906 $aBOOK 912 $a9910300157403321 996 $aIntroduction to Markov processes$933145 997 $aUNINA 999 $aThis Record contains information from the Harvard Library Bibliographic Dataset, which is provided by the Harvard Library under its Bibliographic Dataset Use Terms and includes data made available by, among others the Library of Congress