LEADER 03095nam 2200637 a 450 001 9910130870803321 005 20200520144314.0 010 $a1-283-20346-4 010 $a9786613203465 010 $a1-119-97017-2 010 $a0-470-65935-1 010 $a0-470-65679-4 035 $a(CKB)3460000000000125 035 $a(EBL)711788 035 $a(OCoLC)711780324 035 $a(SSID)ssj0000541431 035 $a(PQKBManifestationID)12181599 035 $a(PQKBTitleCode)TC0000541431 035 $a(PQKBWorkID)10499052 035 $a(PQKB)10412482 035 $a(MiAaPQ)EBC711788 035 $a(Au-PeEL)EBL711788 035 $a(CaPaEBR)ebr10484890 035 $a(CaONFJC)MIL320346 035 $a(PPN)243368658 035 $a(EXLCZ)993460000000000125 100 $a20101221d2011 uy 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 00$aSolid state characterization of pharmaceuticals$b[electronic resource] /$feditors, Richard A. Storey, Ingvar Yme?n 210 $aChichester, U.K. $cJohn Wiley & Sons$d2011 215 $a1 online resource (528 p.) 300 $aDescription based upon print version of record. 311 $a1-4051-3494-1 320 $aIncludes bibliographical references and index. 327 $aIntroduction to the solid state : physical properties and processes -- X-ray diffraction -- Spectroscopic characterisation -- Dielectric spectroscopy and thermally stimulated current spectroscopy : use in the characterisation of solid state pharmaceutical systems -- Solid state characterisation of pharmaceuticals -- Calorimetric methods : solution calorimetry -- Vapour sorption for bulk and surface analysis -- Microscopy -- Mechanical properties of pharmaceutical materials -- Particle size assessment -- Computational polymorph prediction -- Patenting of inventions relating to polymorphs -- A 'roadmap' to solid form selection. 330 $aThe field of solid state characterization is central to the pharmaceutical industry, as drug products are, in an overwhelming number of cases, produced as solid materials. Selection of the optimum solid form is a critical aspect of the development of pharmaceutical compounds, due to their ability to exist in more than one form or crystal structure (polymorphism). These polymorphs exhibit different physical properties which can affect their biopharmaceutical properties. This book provides an up-to-date review of the current techniques used to characterize pharmaceutical solids. Ensuring balan 606 $aSolid dosage forms 606 $aDrugs$xDesign 606 $aPharmaceutical chemistry 615 0$aSolid dosage forms. 615 0$aDrugs$xDesign. 615 0$aPharmaceutical chemistry. 676 $a615/.19 701 $aStorey$b Richard A$0109522 701 $aYmen$b Ingvar$0958660 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910130870803321 996 $aSolid state characterization of pharmaceuticals$92172256 997 $aUNINA