03095nam 2200637 a 450 991013087080332120200520144314.01-283-20346-497866132034651-119-97017-20-470-65935-10-470-65679-4(CKB)3460000000000125(EBL)711788(OCoLC)711780324(SSID)ssj0000541431(PQKBManifestationID)12181599(PQKBTitleCode)TC0000541431(PQKBWorkID)10499052(PQKB)10412482(MiAaPQ)EBC711788(Au-PeEL)EBL711788(CaPaEBR)ebr10484890(CaONFJC)MIL320346(PPN)243368658(EXLCZ)99346000000000012520101221d2011 uy 0engur|n|---|||||txtccrSolid state characterization of pharmaceuticals[electronic resource] /editors, Richard A. Storey, Ingvar YménChichester, U.K. John Wiley & Sons20111 online resource (528 p.)Description based upon print version of record.1-4051-3494-1 Includes bibliographical references and index.Introduction to the solid state : physical properties and processes -- X-ray diffraction -- Spectroscopic characterisation -- Dielectric spectroscopy and thermally stimulated current spectroscopy : use in the characterisation of solid state pharmaceutical systems -- Solid state characterisation of pharmaceuticals -- Calorimetric methods : solution calorimetry -- Vapour sorption for bulk and surface analysis -- Microscopy -- Mechanical properties of pharmaceutical materials -- Particle size assessment -- Computational polymorph prediction -- Patenting of inventions relating to polymorphs -- A 'roadmap' to solid form selection.The field of solid state characterization is central to the pharmaceutical industry, as drug products are, in an overwhelming number of cases, produced as solid materials. Selection of the optimum solid form is a critical aspect of the development of pharmaceutical compounds, due to their ability to exist in more than one form or crystal structure (polymorphism). These polymorphs exhibit different physical properties which can affect their biopharmaceutical properties. This book provides an up-to-date review of the current techniques used to characterize pharmaceutical solids. Ensuring balanSolid dosage formsDrugsDesignPharmaceutical chemistrySolid dosage forms.DrugsDesign.Pharmaceutical chemistry.615/.19Storey Richard A109522Ymen Ingvar958660MiAaPQMiAaPQMiAaPQBOOK9910130870803321Solid state characterization of pharmaceuticals2172256UNINA