Radiation dose reconstruction for epidemiologic uses / / Committee on an Assessment of CDC Radiation Studies, Board on Radiation Effects Research, Commission on Life Sciences, National Research Council

• Pubblicazione: Washington, DC, : National Academy Press, 1995
• Edizione: 1st ed.
• Descrizione fisica: 1 online resource (150 p.)
• Disciplina: 616.9/897
• Soggetto topico: Radiation injuries - Epidemiology - Statistical methods; Radiation dosimetry; Radiation Injuries - epidemiology; Dose-Response Relationship, Radiation; Radioactive Hazard Release; Radiometry
• Note generali: Bibliographic Level Mode of Issuance: Monograph
• Nota di bibliografia: Includes bibliographical references (p. 93-101) and index.
• Nota di contenuto: Radiation Dose Reconstruction for Epidemiologic Uses -- Copyright -- Preface -- Contents -- Executive Summary -- 1 Background -- 2 Introduction -- ELEMENTS OF DOSE RECONSTRUCTION -- TECHNICAL ASPECTS OF DOSE RECONSTRUCTION -- STRUCTURE OF A SCOPING STUDY -- PUBLIC INVOLVEMENT -- SUMMARY AND RECOMMENDATIONS -- NOTE -- 3 Estimating and Confirming The Source Term -- APPROACH TO SOURCE TERM ANALYSIS -- DATA REQUIREMENTS FOR SOURCE TERM ANALYSIS -- EPISODIC RELEASES -- SOURCES OF INFORMATION -- BIAS AND UNCERTAINTY IN RELEASE ESTIMATES -- GAPS IN RELEASE DATA -- SUMMARY AND RECOMMENDATIONS -- 4 Environmental Pathways -- TRANSPORT OF RADIONUCLIDES AND OTHER CONTAMINANTS -- Direct Releases to the Atmosphere -- Direct Releases to the Hydrosphere -- FURTHER CONSIDERATIONS -- Appropriate Use of Mathematical Models -- Uncertainty Analysis -- SUMMARY AND RECOMMENDATIONS -- 5 Radiation Dose Assessment -- SOURCES OF EXPOSURE -- Ambient Exposure -- Inhalation Exposure -- Ingestion Exposure -- POTENTIAL CONSEQUENCES OF RADIATION EXPOSURE -- PRELIMINARY DOSE ASSESSMENT -- COMPREHENSIVE DOSE ASSESSMENT -- INDIVIDUAL DOSE ASSESSMENT -- UNCERTAINTY -- SUMMARY AND RECOMMENDATIONS -- 6 Biologic Dosimetry and Biologic Markers -- MARKERS OF EXPOSURE AND DOSE -- Cytogenetic Markers -- Genetic or Molecular Markers -- Combined Biologic-Maker Assays -- MARKERS OF EFFECT -- MARKERS OF SUSCEPTIBILITY -- MARKERS IN RETROSPECTIVE DOSIMETRY -- MARKERS IN EPIDEMIOLOGY -- SUMMARY AND RECOMMENDATIONS -- 7 Epidemiologic Considerations -- QUANTITATIVE RISK ASSESSMENT: STRENGTHS AND LIMITATIONS OF EPIDEMIOLOGIC STUDIES -- EPIDEMIOLOGY AND DOSE RECONSTRUCTION -- STUDY DESIGN -- Study Types -- Statistical Power -- Outcomes -- Population Identification and Follow-Up -- Bias and Confounding -- Statistical Analysis -- Uncertainty and Misclassification -- SUMMARY AND RECOMMENDATIONS. ; 8 Priority Criteria for Dose Assessment Studies -- BASIC CRITERIA -- DECISION CRITERIA -- FINAL RANKING -- SUMMARY AND RECOMMENDATIONS -- 9 Conclusions -- 10 Literature Cited -- Appendix A Representative Dose Reconstruction Studies -- NEVADA TEST SITE -- CHERNOBYL -- THREE MILE ISLAND -- FERNALD -- HANFORD -- TECHA RIVER -- GOIANIA -- NOTES -- Appendix B Workshop Agenda -- DOSE RECONSTRUCTION FOR EPIDEMIOLOGIC USES AGENDA -- Appendix C Workshop Participants -- KEYNOTE SPEAKERS -- SOURCE TERM ESTIMATION -- ENVIRONMENTAL PATHWAYS -- BIOMARKERS -- RADIATION DOSE ASSESSMENT -- EPIDEMIOLOGY -- Appendix D Glossary -- Index.
• Sommario/riassunto: Growing public concern about releases of radiation into the environment has focused attention on the measurement of exposure of people living near nuclear weapons production facilities or in areas affected by accidental releases of radiation. Radiation-Dose Reconstruction for Epidemiologic Uses responds to the need for criteria for dose reconstruction studies, particularly if the doses are to be useful in epidemiology. This book provides specific and practical recommendations for whether, when, and how studies should be conducted, with an emphasis on public participation. Based on the expertise of scientists involved in dozens of dose reconstruction projects, this volume Provides an overview of the basic requirements and technical aspects of dose reconstruction. Presents lessons to be learned from dose reconstructions after Chernobyl, Three Mile Island, and elsewhere. Explores the potential benefits and limitations of biological markers. Discusses how to establish the "source term"--that is, to determine what was released. Explores methods for identifying the environmental pathways by which radiation reaches the body. Offers details on three major categories of dose assessment.
• Titolo autorizzato: Radiation dose reconstruction for epidemiologic uses
• ISBN: 9786610211043; 9780309176835; 0309176832; 9781280211041; 1280211040; 9780309587136; 0309587131; 9780585002392; 0585002398
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910961798603321
• Lo trovi qui: Univ. Federico II