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Titolo: |
Candida and candidiasis [[electronic resource] /] / edited by Richard A. Calderone, Cornelius J. Clancy
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Pubblicazione: | Washington, DC, : ASM Press, c2012 |
Edizione: | 2nd ed. |
Descrizione fisica: | 1 online resource (544 p.) |
Disciplina: | 616.969 |
Soggetto topico: | Candidiasis |
Candida | |
Altri autori: |
CalderoneRichard A. <1942->
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Note generali: | Description based upon print version of record. |
Nota di bibliografia: | Includes bibliographical references and index. |
Nota di contenuto: | Cover; Contents; Contributors; Preface; 1 Candida: What Should Clinicians and Scientists Be Talking About?; SECTION I: THE ORGANISMS, THEIR GENOMICS, AND VARIABILITY; 2 An Introduction to the Medically Important Candida Species; 3 Comparative Genomics of Candida Species; 4 The Genetic Code of the Candida CTG Clade; 5 Genome Instability and DNA Repair; 6 Switching and Mating; 7 Detection and Clinical Significance of Variability among Candida Isolates; 8 Cell Cycle and Growth Control in Candida Species; SECTION II: HOST-PATHOGEN INTERACTIONS (THE HOST); 9 Immunology of Invasive Candidiasis |
10 Mucosal Immunity to Candida albicans11 Innate Immunity to Candida Infections; 12 Vaccines and Passive Immunity against Candidiasis; 13 Salivary Histatins: Structure, Function, and Mechanisms of Antifungal Activity; SECTION III: HOST-PATHOGEN INTERACTIONS THE PATHOGEN); 14 The Cell Wall: Glycoproteins, Remodeling, and Regulation; 15 Stress Responses in Candida; 16 Adhesins in Opportunistic Fungal Pathogens; 17 Encounters with Mammalian Cells: Survival Strategies of Candida Species; 18 Gene Expression during the Distinct Stages of Candidiasis; 19 Biofilm Formation in Candida albicans | |
20 Candida spp. in Microbial Populations and Communities: Molecular Interactions and Biological Importance21 Back to the Future: Candida Mitochondria and Energetics; SECTION IV: ANTIFUNGAL DRUGS, DRUG RESISTANCE, AND DISCOVERY; 22 Antifungals: Drug Class, Mechanisms of Action, Pharmacokinetics/Pharmacodynamics, Drug-Drug Interactions, Toxicity, and Clinical Use; 23 The Impact of Antifungal Drug Resistance in the Clinic; 24 Insights in Antifungal Drug Discovery; 25 Multidrug Resistance Transcriptional Regulatory Networks in Candida | |
SECTION V: CANDIDIASIS, EVOLVING DIAGNOSTICS, AND TREATMENT PARADIGMS26 Mucosal Candidiasis; 27 Systemic Candidiasis: Candidemia and Deep-Organ Infections; 28 New Developments in Diagnostics and Management of Invasive Candidiasis; 29 The Epidemiology of Invasive Candidiasis; SECTION VI: COOL TOOLS FOR RESEARCH; 30 Cool Tools 1: Development and Application of a Candida albicans Two-Hybrid System; 31 Cool Tools 2: Development of a Candida albicans Cell Surface Protein Microarray; 32 Cool Tools 3: Large-Scale Genetic Interaction Screening in Candida albicans | |
33 Cool Tools 4: Imaging Candida Infections in the Live Host34 Cool Tools 5: The Candida albicans ORFeome Project; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; V; W; X; Y; Z | |
Sommario/riassunto: | The underlying mechanisms of Candida and candidiasis and promising new directions in drug discovery and treatment. |
Titolo autorizzato: | Candida and candidiasis ![]() |
ISBN: | 1-68367-095-7 |
1-283-65648-5 | |
1-55581-717-3 | |
Formato: | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione: | Inglese |
Record Nr.: | 9910829806003321 |
Lo trovi qui: | Univ. Federico II |
Opac: | Controlla la disponibilità qui |