{"text_format":"2","workbook":"xls","n_sheets":1,"sheets":["report2"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":1,"defined_names":1,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"run_cost":"one","rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"report2","index":0,"n_rows":23,"n_cols":5,"rows_kept":23,"cut":false,"hidden":false,"merged":[[0,2,0,3],[0,4,0,5],[1,2,1,3],[1,4,1,5],[2,2,2,3],[3,2,3,3],[6,2,6,3],[7,2,7,3],[8,2,8,3],[9,2,9,3],[11,2,11,3],[12,2,12,3],[16,2,16,3]],"flags":["formulas_cached_only"]}
[null,"1.","Record Nr.",null,"UNINA9910829806003321"]
[null,null,"Titolo",null,"Candida and candidiasis [[electronic resource] /] / edited by Richard A. Calderone, Cornelius J. Clancy"]
[null,null,"Pubbl/distr/stampa",null,"Washington, DC, : ASM Press, c2012"]
[null,null,"ISBN",null,"1-68367-095-7"]
[{"$nulls":4},"1-283-65648-5"]
[{"$nulls":4},"1-55581-717-3"]
[null,null,"Edizione",null,"[2nd ed.]"]
[null,null,"Descrizione fisica",null,"1 online resource (544 p.)"]
[null,null,"Disciplina",null,"616.969"]
[null,null,"Soggetti",null,"Candidiasis"]
[{"$nulls":4},"Candida"]
[null,null,"Lingua di pubblicazione",null,"Inglese"]
[null,null,"Formato",null,"Materiale a stampa"]
[null,null,null,"Livello bibliografico","Monografia"]
[null,null,null,"Note generali","Description based upon print version of record."]
[null,null,null,"Nota di bibliografia","Includes bibliographical references and index."]
[null,null,"Nota di contenuto",null,"Cover; Contents; Contributors; Preface; 1 Candida: What Should Clinicians and Scientists Be Talking About?; SECTION I: THE ORGANISMS, THEIR GENOMICS, AND VARIABILITY; 2 An Introduction to the Medically Important Candida Species; 3 Comparative Genomics of Candida Species; 4 The Genetic Code of the Candida CTG Clade; 5 Genome Instability and DNA Repair; 6 Switching and Mating; 7 Detection and Clinical Significance of Variability among Candida Isolates; 8 Cell Cycle and Growth Control in Candida Species; SECTION II: HOST-PATHOGEN INTERACTIONS (THE HOST); 9 Immunology of Invasive Candidiasis"]
[{"$nulls":4},"10 Mucosal Immunity to Candida albicans11 Innate Immunity to Candida Infections; 12 Vaccines and Passive Immunity against Candidiasis; 13 Salivary Histatins: Structure, Function, and Mechanisms of Antifungal Activity; SECTION III: HOST-PATHOGEN INTERACTIONS THE PATHOGEN); 14 The Cell Wall: Glycoproteins, Remodeling, and Regulation; 15 Stress Responses in Candida; 16 Adhesins in Opportunistic Fungal Pathogens; 17 Encounters with Mammalian Cells: Survival Strategies of Candida Species; 18 Gene Expression during the Distinct Stages of Candidiasis; 19 Biofilm Formation in Candida albicans"]
[{"$nulls":4},"20 Candida spp. in Microbial Populations and Communities: Molecular Interactions and Biological Importance21 Back to the Future: Candida Mitochondria and Energetics; SECTION IV: ANTIFUNGAL DRUGS, DRUG RESISTANCE, AND DISCOVERY; 22 Antifungals: Drug Class, Mechanisms "]
[{"$nulls":4},"of Action, Pharmacokinetics/Pharmacodynamics, Drug-Drug Interactions, Toxicity, and Clinical Use; 23 The Impact of Antifungal Drug Resistance in the Clinic; 24 Insights in Antifungal Drug Discovery; 25 Multidrug Resistance Transcriptional Regulatory Networks in Candida"]
[{"$nulls":4},"SECTION V: CANDIDIASIS, EVOLVING DIAGNOSTICS, AND TREATMENT PARADIGMS26 Mucosal Candidiasis; 27 Systemic Candidiasis: Candidemia and Deep-Organ Infections; 28 New Developments in Diagnostics and Management of Invasive Candidiasis; 29 The Epidemiology of Invasive Candidiasis; SECTION VI: COOL TOOLS FOR RESEARCH; 30 Cool Tools 1: Development and Application of a Candida albicans Two-Hybrid System; 31 Cool Tools 2: Development of a Candida albicans Cell Surface Protein Microarray; 32 Cool Tools 3: Large-Scale Genetic Interaction Screening in Candida albicans"]
[{"$nulls":4},"33 Cool Tools 4: Imaging Candida Infections in the Live Host34 Cool Tools 5: The Candida albicans ORFeome Project; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; V; W; X; Y; Z"]
[null,null,null,"Sommario/riassunto","The underlying mechanisms of Candida and candidiasis and promising new directions in drug discovery and treatment."]