Metal-carbon bonds in enzymes and cofactors / / edited by Astrid Sigel, Helmut Sigel, and Roland K.O. Sigel
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| Titolo: |
Metal-carbon bonds in enzymes and cofactors / / edited by Astrid Sigel, Helmut Sigel, and Roland K.O. Sigel
|
| Pubblicazione: | Cambridge, UK : , : RSC Publishing, , 2009 |
| Descrizione fisica: | 1 online resource |
| Disciplina: | 572.7 |
| Soggetto topico: | Metalloenzymes |
| Coenzymes | |
| Organometallic compounds | |
| Vitamin B12 | |
| Persona (resp. second.): | SigelAstrid |
| SigelHelmut | |
| SigelRoland K. O. | |
| Nota di bibliografia: | Includes bibliographical references and indexes. |
| Nota di contenuto: | Organometallic chemistry of B12 coenzymes -- Cobalamin- and corrinoid-dependent enzymes -- Nickel-alkyl bond formation in the active site of methyl-coenzyme M reductase -- Nickel-carbon bonds in acetyl-coenzyme a synthases/carbon monoxide dehydrogenases -- Structure and function of [NiFe]-hydro-genases -- Carbon monoxide and cyanide ligands in the active site of [FeFe]-hydrogenases -- Carbon monoxide as intrinsic ligand to iron in the active site of [Fe]-hydrogenase -- Dual role of heme as cofactor and substrate in the biosynthesis of carbon monoxide -- Copper-carbon bonds in mechanistic and structural probing of proteins as well as in situations where copper is a catalytic or receptor site -- Interaction of cyanide with enzymes containing vanadium, manganese, non-heme iron, and zinc -- Reaction mechanism of the molybdenum hydroxylase xanthine oxidoreductase: evidence against the formation of intermediates having metal-carbon bonds. |
| Sommario/riassunto: | The occurrence of a wide variety of metal-carbon bonds in living organisms, ranging from bacteria to humans, is only recently recognized. Of course, the historical examples are the B12 coenzymes containing cobalt-carbon bonds, but now such bonds are also known for nickel, iron, copper, and other transition metal ions. There is no other comparable book; MILS-6, written by 17 experts, summarizes the most recent insights into this fascinating topic. |
| Titolo autorizzato: | Metal-carbon bonds in enzymes and cofactors |
| ISBN: | 3-11-043658-2 |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910797445503321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |
Serie:
Metal ions in life sciences ; ; v. 6.