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010   $a3-11-043658-2
024 7 $a10.1515/9783110436587
035   $a(CKB)3710000000455826
035   $a(DE-B1597)456526
035   $a(OCoLC)979746048
035   $a(DE-B1597)9783110436587
035   $a(MiAaPQ)EBC5024742
035   $a(Au-PeEL)EBL5024742
035   $a(CaPaEBR)ebr11567603
035   $a(EXLCZ)993710000000455826
100   $a20110504d2009      uy|            0
101 0 $aeng
135   $aur|||||||||||
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aMetal-carbon bonds in enzymes and cofactors /$fedited by Astrid Sigel, Helmut Sigel, and Roland K.O. Sigel
210  1$aCambridge, UK :$cRSC Publishing,$d2009.
215   $a1 online resource
225 1 $aMetal ions in life sciences,$x1559-0836 ;$vvolume 6
311   $a3-11-044279-5 
320   $aIncludes bibliographical references and indexes.
327   $aOrganometallic chemistry of B12 coenzymes -- Cobalamin- and corrinoid-dependent enzymes -- Nickel-alkyl bond formation in the active site of methyl-coenzyme M reductase -- Nickel-carbon bonds in acetyl-coenzyme a synthases/carbon monoxide dehydrogenases -- Structure and function of [NiFe]-hydro-genases -- Carbon monoxide and cyanide ligands in the active site of [FeFe]-hydrogenases -- Carbon monoxide as intrinsic ligand to iron in the active site of [Fe]-hydrogenase -- Dual role of heme as cofactor and substrate in the biosynthesis of carbon monoxide -- Copper-carbon bonds in mechanistic and structural probing of proteins as well as in situations where copper is a catalytic or receptor site -- Interaction of cyanide with enzymes containing vanadium, manganese, non-heme iron, and zinc -- Reaction mechanism of the molybdenum hydroxylase xanthine oxidoreductase: evidence against the formation of intermediates having metal-carbon bonds.
330   $aThe occurrence of a wide variety of metal-carbon bonds in living organisms, ranging from bacteria to humans, is only recently recognized. Of course, the historical examples are the B12 coenzymes containing cobalt-carbon bonds, but now such bonds are also known for nickel, iron, copper, and other transition metal ions. There is no other comparable book; MILS-6, written by 17 experts, summarizes the most recent insights into this fascinating topic.
410  0$aMetal ions in life sciences ;$vv. 6.
606   $aMetalloenzymes
606   $aCoenzymes
606   $aOrganometallic compounds
606   $aVitamin B12
615  0$aMetalloenzymes.
615  0$aCoenzymes.
615  0$aOrganometallic compounds.
615  0$aVitamin B12.
676   $a572.7
702   $aSigel$b Astrid
702   $aSigel$b Helmut
702   $aSigel$b Roland K. O.
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910797445503321
996   $aMetal-carbon bonds in enzymes and cofactors$93841465
997   $aUNINA