Total Synthesis of (±)-Maoecrystal V / / by Jianxian Gong

• Autore: Gong Jianxian
• Pubblicazione: Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014
• Edizione: 1st ed. 2014.
• Descrizione fisica: 1 online resource (146 p.)
• Disciplina: 547.7; 547.70459
• Soggetto topico: Organic chemistry; Medicinal chemistry; Catalysis; Organic Chemistry; Medicinal Chemistry
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Inclues bibliographical references.
• Nota di contenuto: Research Background for Natural Product Maoecrystal V and Its Family -- The Model Study of Natural Product Maoecrystal V -- The total synthesis study of Maoecrystal V -- Summary.
• Sommario/riassunto: In this thesis, the author describes the total synthesis of natural product Maoecrystal V in detail. In the first part of the thesis, the author introduces the research background and reviews the research progress in total synthesis of Maoecrystal V. In the second part, the author develops a novel and concise approach for the stereoselective construction of the tetracyclic model system of Maoecrystal V. The model system is accomplished in 8 steps with 20% yield. In the third part, the author describes the first successful total synthesis of Maoecrystal V and investigates four strategies for constructing the key tetrahydrofuran oxa-bridge skeleton. The total synthesis starts from a known compound and is accomplished in 17 steps with 1.2% yield. The successful total synthesis of Maoecrystal V will contribute to the development of efficient synthetic strategies for natural products and other compounds with complex structures.
• Titolo autorizzato: Total Synthesis of (±)-Maoecrystal V
• ISBN: 3-642-54304-9
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910298642003321
• Lo trovi qui: Univ. Federico II
• Serie: Springer Theses, Recognizing Outstanding Ph.D. Research, . 2190-5053