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Comprehensive systems biomedicine [[electronic resource] /] / topic editors Enrico Capobianco and Pietro Lió
Comprehensive systems biomedicine [[electronic resource] /] / topic editors Enrico Capobianco and Pietro Lió
Autore Pietro Lio
Pubbl/distr/stampa Frontiers Media SA, 2014
Descrizione fisica 1 online resource (113 pages) : illustrations; digital, PDF file(s)
Collana Frontiers research topics
Soggetto topico Genetics
Biology - General
Biology
Health & Biological Sciences
Soggetto non controllato inference
systems biomedicine
big data
translational science
paradigm shift
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910137237103321
Pietro Lio  
Frontiers Media SA, 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Concepts of genetics / / Michael A. Palladino [and four others]
Concepts of genetics / / Michael A. Palladino [and four others]
Autore Palladino Michael Angelo
Edizione [Eleventh, global edition.]
Pubbl/distr/stampa Boston : , : Pearson, , [2016]
Descrizione fisica 1 online resource (893 pages) : illustrations (some color)
Disciplina 575.1
Collana Always learning
Soggetto topico Genetics
ISBN 1-292-07727-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover -- Title Page -- Copyright Page -- Dedication -- About the Authors -- Brief Contents -- Explore Cutting Edge Topics -- Explore Classic and Modern Approaches -- Learn and Practice Problem Solving -- Succeed with MasteringGenetics -- Contents -- Preface -- 1. Introduction to Genetics -- 1.1. Genetics Has a Rich and Interesting History -- 1600-1850: The Dawn of Modern Biology -- Charles Darwin and Evolution -- 1.2. Genetics Progressed from Mendel to DNA in Less Than a Century -- Mendel's Work on Transmission of Traits -- The Chromosome Theory of Inheritance: Uniting Mendel and Meiosis -- Genetic Variation -- The Search for the Chemical Nature of Genes: DNA or Protein? -- 1.3. Discovery of the Double Helix Launched the Era of Molecular Genetics -- The Structure of DNA and RNA -- Gene Expression: From DNA to Phenotype -- Proteins and Biological Function -- Linking Genotype to Phenotype: Sickle-Cell Anemia -- 1.4. Development of Recombinant DNA Technology Began the Era of DNA Cloning -- 1.5. The Impact of Biotechnology is Continually Expanding -- Plants, Animals, and the Food Supply -- Biotechnology in Genetics and Medicine -- 1.6. Genomics, Proteomics, and Bioinformatics are New and Expanding Fields -- Modern Approaches to Understanding Gene Function -- 1.7. Genetic Studies Rely on the Use of Model Organisms -- The Modern Set of Genetic Model Organisms -- Model Organisms and Human Diseases -- 1.8. We Live in the Age of Genetics -- The Nobel Prize and Genetics -- Genetics and Society -- The Scientific and Ethical Implications of Modern Genetics -- Internet Resources for Learning About Genomics, Bioinformatics, and Proteomics -- Summary Points -- Case Study: Extending Essential Ideas of Genetics Beyond the Classroom -- Problems and Discussion Questions -- 2. Mitosis and Meiosis -- 2.1. Cell Structure Is Closely Tied to Genetic Function.
2.2. Chromosomes Exist in Homologous Pairs in Diploid Organisms -- 2.3. Mitosis Partitions Chromosomes into Dividing Cells -- Interphase and the Cell Cycle -- Prophase -- Prometaphase and Metaphase -- Anaphase -- Telophase -- Cell-Cycle Regulation and Checkpoints -- 2.4. Meiosis Reduces the Chromosome Number from Diploid to Haploid in Germ Cells and Spores -- An Overview of Meiosis -- The First Meiotic Division: Prophase I -- Metaphase, Anaphase, and Telophase I -- The Second Meiotic Division -- 2.5. The Development of Gametes Varies in Spermatogenesis Compared to Oogenesis -- 2.6. Meiosis is Critical to Sexual Reproduction in All Diploid Organisms -- 2.7. Electron Microscopy Has Revealed the Physical Structure of Mitotic and Meiotic Chromosomes -- Pubmed: Exploring and Retrieving Biomedical Literature -- Case Study: Timing is Everything -- Summary Points -- Insights and Solutions -- Problems and Discussion Questions -- 3. Mendelian Genetics -- 3.1. Mendel Used a Model Experimental Approach to Study Patterns of Inheritance -- 3.2. The Monohybrid Cross Reveals How One Trait Is Transmitted from Generation to Generation -- Mendel's First Three Postulates -- Modern Genetic Terminology -- Mendel's Analytical Approach -- Punnett Squares -- The Testcross: One Character -- 3.3. Mendel's Dihybrid Cross Generated a Unique F2 Ratio -- Mendel's Fourth Postulate: Independent Assortment -- The Testcross: Two Characters -- Identifying Mendel's Gene for Regulating White Flower Color in Peas -- 3.4. The Trihybrid Cross Demonstrates That Mendel's Principles Apply to Inheritance of Multiple Traits -- The Forked-Line Method, or Branch Diagram -- 3.5. Mendel's Work was Rediscovered in the Early Twentieth Century -- The Chromosomal Theory of Inheritance -- Unit Factors, Genes, and Homologous Chromosomes -- 3.6. Independent Assortment Leads to Extensive Genetic Variation.
3.7. Laws of Probability Help to Explain Genetic Events -- The Binomial Theorem -- 3.8. Chi-Square Analysis Evaluates the Influence of Chance on Genetic Data -- Chi-Square Calculations and the Null Hypothesis -- Interpreting Probability Values -- 3.9. Pedigrees Reveal Patterns of Inheritance of Human Traits -- Pedigree Conventions -- Pedigree Analysis -- 3.10. Mutant Phenotypes Have Been Examined at the Molecular Level -- How Mendel's Peas Become Wrinkled: A Molecular Explanation -- Tay-Sachs Disease: The Molecular Basis of a Recessive Disorder in Humans -- Online Mendelian Inheritance in Man -- Case Study: To Test or not to Test -- Summary Points -- Insights and Solutions -- Problems and Discussion Questions -- 4. Extensions of Mendelian Genetics -- 4.1. Alleles Alter Phenotypes in Different Ways -- 4.2. Geneticists Use a Variety of Symbols for Alleles -- 4.3. Neither Allele is Dominant in Incomplete, or Partial, Dominance -- 4.4. In Codominance, the Influence of Both Alleles in a Heterozygote Is Clearly Evident -- 4.5. Multiple Alleles of a Gene May Exist in a Population -- The ABO Blood Groups -- The A and B Antigens -- The Bombay Phenotype -- The White Locus in Drosophila -- 4.6. Lethal Alleles Represent Essential Genes -- The Molecular Basis of Dominance, Recessiveness, and Lethality: The Agouti Gene -- 4.7. Combinations of Two Gene Pairs with Two Modes of Inheritance Modify the 9:3:3:1 Ratio -- 4.8. Phenotypes are Often Affected by More Than One Gene -- Epistasis -- Novel Phenotypes -- Other Modified Dihybrid Ratios -- 4.9. Complementation Analysis Can Determine if Two Mutations Causing a Similar Phenotype are Alleles of the Same Gene -- 4.10. Expression of a Single Gene May Have Multiple Effects -- 4.11. X-Linkage Describes Genes on the X Chromosome -- X-Linkage in Drosophila -- X-Linkage in Humans.
4.12. In Sex-Limited and Sex-Influenced Inheritance, an Individual's Sex Influences the Phenotype -- 4.13. Genetic Background and the Environment May Alter Phenotypic Expression -- Penetrance and Expressivity -- Genetic Background: Position Effects -- Temperature Effects-An Introduction to Conditional Mutations -- Nutritional Effects -- Onset of Genetic Expression -- Genetic Anticipation -- Genomic (Parental) Imprinting and Gene Silencing -- Improving the Genetic Fate of Purebred Dogs -- Case Study: But he isn't Deaf -- Summary Points -- Insights and Solutions -- Problems and Discussion Questions -- 5. Chromosome Mapping in Eukaryotes -- 5.1. Genes Linked on the Same Chromosome Segregate Together -- The Linkage Ratio -- 5.2. Crossing Over Serves as the Basis for Determining the Distance between Genes in Chromosome Mapping -- Morgan and Crossing Over -- Sturtevant and Mapping -- Single Crossovers -- 5.3. Determining the Gene Sequence during Mapping Requires the Analysis of Multiple Crossovers -- Multiple Exchanges -- Three-Point Mapping in Drosophila -- Determining the Gene Sequence -- A Mapping Problem in Maize -- 5.4. As the Distance Between Two Genes Increases, Mapping Estimates Become More Inaccurate -- Interference and the Coefficient of Coincidence -- 5.5. Drosophila Genes Have Been Extensively Mapped -- 5.6. Lod Score Analysis and Somatic Cell Hybridization Were Historically Important in Creating Human Chromosome Maps -- 5.7. Chromosome Mapping is Now Possible Using DNA Markers and Annotated Computer Databases -- 5.8. Crossing Over Involves a Physical Exchange Between Chromatids -- 5.9. Exchanges Also Occur between Sister Chromatids during Mitosis -- 5.10. Did Mendel Encounter Linkage? -- Human Chromosome Maps on the Internet -- Case Study: Links to Autism -- Summary Points -- Insights and Solutions -- Problems and Discussion Questions.
6. Genetic Analysis and Mapping in Bacteria and Bacteriophages -- 6.1. Bacteria Mutate Spontaneously and Grow at an Exponential Rate -- 6.2. Genetic Recombination Occurs in Bacteria -- Conjugation in Bacteria: The Discovery of F+ and F- Strains -- Hfr Bacteria and Chromosome Mapping -- Recombination in F+ x F- Matings: A Reexamination -- The F' State and Merozygotes -- 6.3. Rec Proteins are Essential to Bacterial Recombination -- 6.4. The F Factor Is an Example of a Plasmid -- 6.5. Transformation Is a Second Process Leading to Genetic Recombination in Bacteria -- The Transformation Process -- Transformation and Linked Genes -- 6.6. Bacteriophages are Bacterial Viruses -- Phage T4: Structure and Life Cycle -- The Plaque Assay -- Lysogeny -- 6.7. Transduction Is Virus-Mediated Bacterial DNA Transfer -- The Lederberg-Zinder Experiment -- The Nature of Transduction -- Transduction and Mapping -- 6.8. Bacteriophages Undergo Intergenic Recombination -- Bacteriophage Mutations -- Mapping in Bacteriophages -- 6.9. Intragenic Recombination Occurs in Phage T4 -- The rll Locus of Phage T4 -- Complementation by rll Mutations -- Recombinational Analysis -- Deletion Testing of the rll Locus -- The rll Gene Map -- From Cholera Genes to Edible Vaccines -- Case Study: To Treat or not to Treat -- Summary Points -- Insights and Solutions -- Problems and Discussion Questions -- 7. Sex Determination and Sex Chromosomes -- 7.1. Life Cycles Depend on Sexual Differentiation -- Chlamydomonas -- Zea Mays -- Caenorhabditis Elegans -- 7.2. X and Y Chromosomes Were First Linked to Sex Determination Early in the Twentieth Century -- 7.3. The Y Chromosome Determines Maleness in Humans -- Klinefelter and Turner Syndromes -- 47,XXX Syndrome -- 47,XYY Condition -- Sexual Differentiation in Humans -- The Y Chromosome and Male Development.
7.4. The Ratio of Males to Females in Humans Is Not 1.0.
Record Nr. UNINA-9910154766303321
Palladino Michael Angelo  
Boston : , : Pearson, , [2016]
Materiale a stampa
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Controversies in science and technology : from maize to menopause
Controversies in science and technology : from maize to menopause
Autore Kleinman Daniel Lee
Pubbl/distr/stampa [Place of publication not identified], : University of Wisconsin Press, 2005
Soggetto topico Biotechnology
Agriculture
Anti-Bacterial Agents
Bioterrorism
Estrogen Replacement Therapy
Menopause
Plants, Genetically Modified
Biology
Health & Biological Sciences
Genetics
ISBN 1-282-26962-3
9786612269622
0-299-20393-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910452059003321
Kleinman Daniel Lee  
[Place of publication not identified], : University of Wisconsin Press, 2005
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Coronavirus Disease 2019 (COVID-19) [[electronic resource] ] : Epidemiology, Pathogenesis, Diagnosis, and Therapeutics / / edited by Shailendra K. Saxena
Coronavirus Disease 2019 (COVID-19) [[electronic resource] ] : Epidemiology, Pathogenesis, Diagnosis, and Therapeutics / / edited by Shailendra K. Saxena
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (224 pages)
Disciplina 614.592414
Collana Medical Virology: From Pathogenesis to Disease Control
Soggetto topico Virology
Parasitology
Immunology
Genetics
Genetics and Genomics
COVID-19
Terapèutica
Soggetto genere / forma Llibres electrònics
ISBN 981-15-4814-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Module 1_Global trends in epidemiology of Coronavirus Disease 2019 (COVID-19) -- Module 2_ Genome organization and Pathogenesis of novel Coronavirus 2019 (SARS-CoV-2) -- Module 3_Host immune response against human SARS-CoV-2 infection -- Module 4_ Emergence and Re-emergence of SARS Coronaviruses -- Module 5_Transmission cycle of SARS-CoV and SARS-CoV-2 -- Module 6_Preparing for the perpetual challenges of pandemics of Coronavirus infections with special focus on SARS-CoV-2. –Module 7_Clinical manifestations and diagnosis of human SARS-CoV-2 infection -- Module 8_ Treatment and Drugs for SARS-CoV-2 -- Module 9_Prevention and control strategies for SARS-CoV-2 infection.
Record Nr. UNINA-9910409696503321
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2020
Materiale a stampa
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Cotton science and processing technology : gene, ginning, garment and green recycling / / Hua Wang, Hafeezullah Memon, editors
Cotton science and processing technology : gene, ginning, garment and green recycling / / Hua Wang, Hafeezullah Memon, editors
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Singapore : , : Springer, , [2020]
Descrizione fisica 1 online resource (XII, 565 p. 314 illus., 238 illus. in color.)
Disciplina 633.51
Collana Textile science and clothing technology
Soggetto topico Cotton
Plant fibers
Genetics
ISBN 981-15-9169-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction to cotton and its seed -- Classification and genetic diversity of cotton (Gossypium) -- Genomic tools to study phylogeny and diversity (in the US and China) -- Agricultural and planting of cotton -- Harvesting and storage of cotton -- Cotton ginning technology (background economics and industry) -- Cotton contamination -- Physical structure, properties and quality of cotton -- Cotton fiber testing (HVI and AFIS) -- Recent advancement in cotton Spinning -- Cotton melange yarn industry -- Cotton and weaving Technology -- Knitting technology for cotton -- Pre-treatment of cotton -- Cotton fiber and yarn dyeing -- Cotton Based Clothing -- Chemical Modification of Cotton for advanced applications -- Cotton as Bio-Materials -- Recycling and LCA of cotton.
Record Nr. UNINA-9910426043403321
Singapore : , : Springer, , [2020]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Crop Production / / edited by Aakash Goyal, Muhammad Asif
Crop Production / / edited by Aakash Goyal, Muhammad Asif
Pubbl/distr/stampa [Place of publication not identified] : , : IntechOpen, , 2013
Descrizione fisica 1 online resource (196 pages)
Disciplina 575.1
Soggetto topico Genetics
ISBN 953-51-5383-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910317735203321
[Place of publication not identified] : , : IntechOpen, , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Current genetics
Current genetics
Pubbl/distr/stampa Heidelberg, : Springer-Verlag
Disciplina 575.105
Soggetto topico Genetics
Génétique
Hefeartige Pilze
Genetik
Molekularbiologie
Mikroorganismus
Zeitschrift
Online-Ressource
Eukaryoten
Soggetto genere / forma Periodical
Periodicals.
Zeitschrift
Online-Publikation
ISSN 1432-0983
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Altri titoli varianti Curr genet
Record Nr. UNISA-996208773503316
Heidelberg, : Springer-Verlag
Materiale a stampa
Lo trovi qui: Univ. di Salerno
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Current genetics
Current genetics
Pubbl/distr/stampa Heidelberg, : Springer-Verlag
Disciplina 575.105
Soggetto topico Genetics
Génétique
Hefeartige Pilze
Genetik
Molekularbiologie
Mikroorganismus
Zeitschrift
Online-Ressource
Eukaryoten
Soggetto genere / forma Periodical
Periodicals.
Zeitschrift
Online-Publikation
ISSN 1432-0983
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Altri titoli varianti Curr genet
Record Nr. UNINA-9910146356803321
Heidelberg, : Springer-Verlag
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Current opinion in genetics & development
Current opinion in genetics & development
Pubbl/distr/stampa [London], : Current Biology, [1991]-
Disciplina 575.1/05
Soggetto topico Genetics
Developmental biology
Developmental genetics
Genetics - Periodicals
Developmental biology - Periodicals
Developmental Biology
Génétique - Périodiques
Biologie du développement - Périodiques
Génétique du développement
Génétique
Biologie du développement
Genetica
Soggetto genere / forma Bibliography
Periodical
bibliographies.
periodicals.
Bibliographies.
Periodicals.
Périodiques.
Soggetto non controllato Genetics
ISSN 1879-0380
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Altri titoli varianti Current opinion in genetics and development
Record Nr. UNINA-9910142556303321
[London], : Current Biology, [1991]-
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Current opinion in genetics & development
Current opinion in genetics & development
Pubbl/distr/stampa [London], : Current Biology, [1991]-
Disciplina 575.1/05
Soggetto topico Genetics
Developmental biology
Developmental genetics
Genetics - Periodicals
Developmental biology - Periodicals
Developmental Biology
Génétique - Périodiques
Biologie du développement - Périodiques
Génétique du développement
Génétique
Biologie du développement
Genetica
Soggetto genere / forma Bibliography
Periodical
bibliographies.
periodicals.
Bibliographies.
Periodicals.
Périodiques.
Soggetto non controllato Genetics
ISSN 1879-0380
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Altri titoli varianti Current opinion in genetics and development
Record Nr. UNISA-996204832603316
[London], : Current Biology, [1991]-
Materiale a stampa
Lo trovi qui: Univ. di Salerno
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