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Aromatic Hydroxyketones: Preparation & Physical Properties : Aromatic Hydroxyketones from Butanone (C4) to Dotriacontanone (C32) / Robert Martin, Jean-Pierre Buisson
| Aromatic Hydroxyketones: Preparation & Physical Properties : Aromatic Hydroxyketones from Butanone (C4) to Dotriacontanone (C32) / Robert Martin, Jean-Pierre Buisson |
| Autore | Martin, Robert |
| Pubbl/distr/stampa | Cham, : Springer, 2015 |
| Descrizione fisica | XXIII, 1449 p. : ill. ; 24 cm |
| Disciplina |
540(Chimica generale)
547(Chimica organica) 615.19(Chimica farmaceutica. Tecnologia farmaceutica. Chimica medica) |
| Altri autori (Persone) | Buisson, Jean-Pierre |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNICAMPANIA-VAN0242670 |
Martin, Robert
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| Cham, : Springer, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Vanvitelli | ||
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The art of drug synthesis / / edited by Douglas S. Johnson, Jie Jack Li
| The art of drug synthesis / / edited by Douglas S. Johnson, Jie Jack Li |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, N.J. : , : Wiley-Interscience, , 2007 |
| Descrizione fisica | 1 online resource (xv, 276 pages) : illustrations |
| Disciplina |
615.19
615/.19 |
| Altri autori (Persone) |
JohnsonDouglas S <1968-> (Douglas Scott)
LiJie Jack |
| Collana | Wiley Series on Drug Synthesis |
| Soggetto topico |
Drugs - Design
Pharmaceutical chemistry |
| ISBN |
1-118-67846-X
1-280-91677-X 9786610916771 0-470-13497-6 0-470-13496-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
THE ART OF DRUG SYNTHESIS; CONTENTS; Foreword; Preface; Contributors; 1 THE ROLE OF MEDICINAL CHEMISTRY IN DRUG DISCOVERY; 1.1 Introduction; 1.2 Hurdles in the Drug Discovery Process; 1.3 The Tools of Medicinal Chemistry; 1.3.1 In Silico Modeling; 1.3.2 Structure-Based Drug Design (SBDD); 1.4 The Role of Synthetic Chemistry in Drug Discovery; References; 2 PROCESS RESEARCH: HOW MUCH? HOW SOON?; 2.1 Introduction; 2.2 Considerations for Successful Scale-up to Tox Batches and Phase I Material; 2.3 Considerations for Phase 2 Material and Beyond; 2.3.1 Reagent Selection; 2.3.2 Solvent Selection
2.3.3 Unit Operations; 2.3.4 Developing Simple, Effective, Efficient Work-ups and Isolations; 2.3.5 The Importance of Physical States; 2.3.6 Route Design and Process Optimization to Minimize COG; 2.4 Summary; References; I CANCER AND INFECTIOUS DISEASES; 3 AROMATASE INHIBITORS FOR BREAST CANCER: EXEMESTANE (AROMASIN®), ANASTROZOLE (ARIMIDEX®), AND LETROZOLE (FEMARA®); 3.1 Introduction; 3.2 Synthesis of Exemestane; 3.3 Synthesis of Anastrozole; 3.4 Synthesis of Letrozole; References 4 QUINOLONE ANTIBIOTICS: LEVOFLOXACIN (LEVAQUIN®), MOXIFLOXACIN (AVELOX®), GEMIFLOXACIN (FACTIVE®), AND GARENOXACIN (T-3811)4.1 Introduction; 4.1.1 Mechanism of Action; 4.1.2 Modes of Resistance; 4.1.3 Structure-Activity Relationship (SAR) and Structure-Toxicity Relationship (STR); 4.1.4 Pharmacokinetics; 4.1.5 Synthetic Approaches; 4.2 Levofloxacin; 4.3 Moxifloxacin; 4.4 Gemifloxacin; 4.5 Garenoxacin (T-3811): A Promising Clinical Candidate; References; 5 TRIAZOLE ANTIFUNGALS: ITRACONAZOLE (SPORANOX®), FLUCONAZOLE (DIFLUCAN®), VORICONAZOLE (VFEND®), AND FOSFLUCONAZOLE (PRODIF®) 5.1 Introduction; 5.2 Synthesis of Itraconazole; 5.3 Synthesis of Fluconazole; 5.4 Synthesis of Voriconazole; 5.5 Synthesis of Fosfluconazole; References; 6 NON-NUCLEOSIDE HIV REVERSE TRANSCRIPTASE INHIBITORS; 6.1 Introduction; 6.2 Synthesis of Nevirapine; 6.3 Synthesis of Efavirenz; 6.4 Synthesis of Delavirdine Mesylate; References; 7 NEURAMINIDASE INHIBITORS FOR INFLUENZA: OSELTAMIVIR PHOSPHATE (TAMIFLU®) AND ZANAMIVIR (RELENZA®); 7.1 Introduction; 7.1.1 Relenza; 7.1.2 Tamiflu; 7.2 Synthesis of Oseltamivir Phosphate (Tamiflu®); 7.3 Synthesis of Zanamivir (Relenza®); References II CARDIOVASCULAR AND METABOLIC DISEASES; 8 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) AGONISTS FOR TYPE 2 DIABETES; 8.1 Introduction; 8.1.1 Insulin; 8.1.2 Sulfonylurea Drugs; 8.1.3 Meglitinides; 8.1.4 Biguanides; 8.1.5 Alpha-Glucosidase Inhibitors; 8.1.6 Thiazolidinediones; 8.2 Synthesis of Rosiglitazone; 8.3 Synthesis of Pioglitazone; 8.4 Synthesis of Muraglitazar; References; 9 ANGIOTENSIN AT(1) ANTAGONISTS FOR HYPERTENSION; 9.1 Introduction; 9.2 Losartan Potassium; 9.2.1 Introduction to Losartan Potassium; 9.2.2 Synthesis of Losartan Potassium; 9.3 Valsartan; 9.3.1 Introduction to Valsartan |
| Record Nr. | UNINA-9910143402603321 |
| Hoboken, N.J. : , : Wiley-Interscience, , 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The art of process chemistry [[electronic resource] /] / edited by Nobuyoshi Yasuda
| The art of process chemistry [[electronic resource] /] / edited by Nobuyoshi Yasuda |
| Pubbl/distr/stampa | Weinheim, Germany, : Wiley-VCH, 2011 |
| Descrizione fisica | 1 online resource (282 p.) |
| Disciplina | 615.19 |
| Altri autori (Persone) | YasudaNobuyoshi |
| Soggetto topico | Pharmaceutical chemistry |
| Soggetto genere / forma | Electronic books. |
| ISBN |
3-527-63358-8
1-282-85998-6 9786612859984 3-527-63356-1 3-527-63357-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Efavirenz®, a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI), and a Previous Structurally Related Development Candidate -- 2. CCR5 Receptor Antagonist -- 3. 5a-Reductase Inhibitors-The Finasteride Story -- 4. Rizatriptan (Maxalt®): A 5-HT1D Receptor Agonist -- 5. SERM : Selective Estrogen Receptor Modulator -- 6. HIV Integrase Inhibitor: Raltegravir -- 7. Cyclopentane-Based NK1 Receptor Antagonist -- 8. Glucokinase Activator -- 9. CB1R Inverse Agonist-Taranabant. |
| Record Nr. | UNINA-9910141037703321 |
| Weinheim, Germany, : Wiley-VCH, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The art of process chemistry [[electronic resource] /] / edited by Nobuyoshi Yasuda
| The art of process chemistry [[electronic resource] /] / edited by Nobuyoshi Yasuda |
| Pubbl/distr/stampa | Weinheim, Germany, : Wiley-VCH, 2011 |
| Descrizione fisica | 1 online resource (282 p.) |
| Disciplina | 615.19 |
| Altri autori (Persone) | YasudaNobuyoshi |
| Soggetto topico | Pharmaceutical chemistry |
| ISBN |
3-527-63358-8
1-282-85998-6 9786612859984 3-527-63356-1 3-527-63357-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Efavirenz®, a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI), and a Previous Structurally Related Development Candidate -- 2. CCR5 Receptor Antagonist -- 3. 5a-Reductase Inhibitors-The Finasteride Story -- 4. Rizatriptan (Maxalt®): A 5-HT1D Receptor Agonist -- 5. SERM : Selective Estrogen Receptor Modulator -- 6. HIV Integrase Inhibitor: Raltegravir -- 7. Cyclopentane-Based NK1 Receptor Antagonist -- 8. Glucokinase Activator -- 9. CB1R Inverse Agonist-Taranabant. |
| Record Nr. | UNINA-9910829838703321 |
| Weinheim, Germany, : Wiley-VCH, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The art of process chemistry [[electronic resource] /] / edited by Nobuyoshi Yasuda
| The art of process chemistry [[electronic resource] /] / edited by Nobuyoshi Yasuda |
| Pubbl/distr/stampa | Weinheim, Germany, : Wiley-VCH, 2011 |
| Descrizione fisica | 1 online resource (282 p.) |
| Disciplina | 615.19 |
| Altri autori (Persone) | YasudaNobuyoshi |
| Soggetto topico | Pharmaceutical chemistry |
| ISBN |
3-527-63358-8
1-282-85998-6 9786612859984 3-527-63356-1 3-527-63357-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Efavirenz®, a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI), and a Previous Structurally Related Development Candidate -- 2. CCR5 Receptor Antagonist -- 3. 5a-Reductase Inhibitors-The Finasteride Story -- 4. Rizatriptan (Maxalt®): A 5-HT1D Receptor Agonist -- 5. SERM : Selective Estrogen Receptor Modulator -- 6. HIV Integrase Inhibitor: Raltegravir -- 7. Cyclopentane-Based NK1 Receptor Antagonist -- 8. Glucokinase Activator -- 9. CB1R Inverse Agonist-Taranabant. |
| Record Nr. | UNINA-9910841407703321 |
| Weinheim, Germany, : Wiley-VCH, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Artemisinin and Nitric Oxide : Mechanisms and Implications in Disease and Health / Qing-Ping Zeng
| Artemisinin and Nitric Oxide : Mechanisms and Implications in Disease and Health / Qing-Ping Zeng |
| Autore | Zeng, Qing-Ping |
| Pubbl/distr/stampa | Berlin, : Springer, 2015 |
| Descrizione fisica | XV, 126 p. : ill. ; 24 cm |
| Disciplina |
618.97(Geriatria)
616.4(Endocrinologia) 540(Chimica generale) 615.19(Chimica farmaceutica. Tecnologia farmaceutica. Chimica medica) 616.7(Ortopedia) 612.6(Gerontologia - Fisiologia umana) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNICAMPANIA-VAN0241790 |
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Zeng, Qing-Ping
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| Berlin, : Springer, 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Vanvitelli | ||
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Artificial Assemblies with Cooperative DNA Recognition : Doctoral Thesis accepted by Kyoto University, Kyoto, Japan / Zutao YU
| Artificial Assemblies with Cooperative DNA Recognition : Doctoral Thesis accepted by Kyoto University, Kyoto, Japan / Zutao YU |
| Autore | Yu, Zutao |
| Pubbl/distr/stampa | Singapore, : Springer, 2020 |
| Descrizione fisica | XV, 136 p. : ill. ; 24 cm |
| Disciplina |
660.6(Biotecnologia. Microbiologia applicata)
540(Chimica generale) 615.19(Chimica farmaceutica. Tecnologia farmaceutica. Chimica medica) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNICAMPANIA-VAN0243986 |
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Yu, Zutao
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| Singapore, : Springer, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Vanvitelli | ||
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Artificial intelligence in drug discovery / Nathan Brown
| Artificial intelligence in drug discovery / Nathan Brown |
| Autore | Brown, Nathan |
| Pubbl/distr/stampa | Cambridge, : Royal Society of Chemistry, 2021 |
| Descrizione fisica | XVII, 405 p. : ill. ; 25 cm |
| Disciplina | 615.19 |
| Soggetto topico | Farmaci - Sperimentazione |
| ISBN | 9781788015479 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISANNIO-NAP0918053 |
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Brown, Nathan
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| Cambridge, : Royal Society of Chemistry, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. del Sannio | ||
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Arzneimitteltherapiesicherheit im spannungsfeld von vollständiger nedikationsübersicht, mündigem Patienten und individualisierter Medikation / / Alexandra Classen [and sixteen others]
| Arzneimitteltherapiesicherheit im spannungsfeld von vollständiger nedikationsübersicht, mündigem Patienten und individualisierter Medikation / / Alexandra Classen [and sixteen others] |
| Pubbl/distr/stampa | Göttingen, [Germany] : , : Cuvillier Verlag, , 2015 |
| Descrizione fisica | 1 online resource (144 pages) |
| Disciplina | 615.19 |
| Collana | Sozialwissenschaftliche Ansätze in der Wirtschaftsinformatik |
| Soggetto topico | Drugs - Therapeutic equivalency |
| ISBN | 3-7369-8115-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ger |
| Record Nr. | UNINA-9910794964803321 |
| Göttingen, [Germany] : , : Cuvillier Verlag, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Arzneimitteltherapiesicherheit im spannungsfeld von vollständiger nedikationsübersicht, mündigem Patienten und individualisierter Medikation / / Alexandra Classen [and sixteen others]
| Arzneimitteltherapiesicherheit im spannungsfeld von vollständiger nedikationsübersicht, mündigem Patienten und individualisierter Medikation / / Alexandra Classen [and sixteen others] |
| Pubbl/distr/stampa | Göttingen, [Germany] : , : Cuvillier Verlag, , 2015 |
| Descrizione fisica | 1 online resource (144 pages) |
| Disciplina | 615.19 |
| Collana | Sozialwissenschaftliche Ansätze in der Wirtschaftsinformatik |
| Soggetto topico | Drugs - Therapeutic equivalency |
| ISBN | 3-7369-8115-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ger |
| Record Nr. | UNINA-9910826759203321 |
| Göttingen, [Germany] : , : Cuvillier Verlag, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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