Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Application of ionic liquids in drug delivery / / Masahiro Goto, Muhammad Moniruzzaman
| Application of ionic liquids in drug delivery / / Masahiro Goto, Muhammad Moniruzzaman |
| Autore | Goto Masahiro |
| Pubbl/distr/stampa | Singapore : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (246 pages) |
| Disciplina | 615.19 |
| Soggetto topico |
Ionic solutions - Therapeutic use
Drug delivery systems |
| ISBN | 981-16-4365-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910495194403321 |
Goto Masahiro
|
||
| Singapore : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Application of Peptide-Based Prodrug Chemistry in Drug Development [[electronic resource] /] / by Arnab De
| Application of Peptide-Based Prodrug Chemistry in Drug Development [[electronic resource] /] / by Arnab De |
| Autore | De Arnab |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (88 p.) |
| Disciplina | 615.19 |
| Collana | SpringerBriefs in Pharmaceutical Science & Drug Development |
| Soggetto topico |
Pharmaceutical technology
Pharmacology Diabetes Pharmaceutical Sciences/Technology Pharmacology/Toxicology |
| ISBN |
1-283-62464-8
9786613937094 1-4614-4875-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Macromolecular (specifically peptide-based) drugs could potentially be highly effective medicines. However they have a relatively short duration of action and variable therapeutic index. An example of such a peptide is Glucagon-like Peptide I which could potentially be used as a revolutionary drug for diabetes. This is because it stimulates insulin only when the blood glucose level is high thereby reducing the risk of hypoglycemia (a significant disadvantage of using insulin is that an insulin overdose is the single most potent cause of life-threatening hypoglycemia). However it’s short duration of action (half-life of 2 minutes in plasma) precludes its therapeutic use. In this volume, the use of novel therapeutics like GLP1 as an alternative to tradition insulin-based drugs in diabetes is described. Application of Peptide-Based Prodrug Chemistry in Drug Development elucidates the traditional concept of prodrugs as “specialized non-toxic protective groups used in a transient manner to alter or to eliminate certain limiting properties in the parent small molecule” (IUPAC definition). It goes on to provide insight into how prodrugs of peptides (with GLP1 as an example) could be appropriately used to extend the biological half life, broaden the therapeutic index of macromolecules and improve the pharmacodynamics of such drugs. Author explains the logic behind designing peptide prodrugs, synthetic procedures and bioassays to examine the conversion of the prodrug to the drug under therapeutic conditions. The prodrugs described slowly convert to the parent drug at physiological conditions of 37C and pH 7.2 driven by their inherent chemical instability without the need of any enzymatic cleavage. The diketopiperazine and diketomorpholine (DKP and DMP) strategies for prodrug conversion are demonstrated in detail with special emphasis on the chemical flexibility that it offers to develop prodrugs with variable time actions. This book will be of useful to chemists, biochemists, medicinal chemists, biologists and people in the medical profession (doctors). It may be used in undergraduate classes but will certainly help post-graduate students and advanced professionals. The author is grateful to Prof. Richard DiMarchi (Standiford H. Cox Professor of Chemistry and the Linda & Jack Gill Chair in Biomolecular Sciences at Indiana University) for valuable suggestions. The foreword for the book has been written by Prof. Jean Martinez, (Legion d'Honneur awarded by the French Republic; Professor of Chemistry and Medicinal Chemistry of the University of Montpellier, France; and Chairman of European Peptide Society, 2002-2010). Table of contents: Introduction -- Aapplication of Prodrug Chemistry to GLP-1 -- Experimental procedures -- Characterization of Prodrugs -- Conclusion. |
| Record Nr. | UNINA-9910438129903321 |
|
De Arnab
|
||
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Application of project management principles to the management of pharmaceutical r&d projects / / Thomas Catalano
| Application of project management principles to the management of pharmaceutical r&d projects / / Thomas Catalano |
| Autore | Catalano Thomas <1942-> |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2020] |
| Descrizione fisica | 1 online resource (XV, 70 p. 29 illus., 10 illus. in color.) |
| Disciplina | 615.19 |
| Collana | SpringerBriefs in Pharmaceutical Science & Drug Development |
| Soggetto topico |
Pharmaceutical technology
Pharmacology Medicine |
| ISBN | 3-030-57527-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Project Management Concepts -- Theory of Constraints.-Project Management Process -- Risk Evaluation Process -- Project Plan Implementation -- Financial Project Management -- Project Outsourcing -- List of Abbreviations -- Index. . |
| Record Nr. | UNINA-9910426056003321 |
|
Catalano Thomas <1942->
|
||
| Cham, Switzerland : , : Springer, , [2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Applications and properties of magnetic nanoparticles / / Paolo Arosio, editor
| Applications and properties of magnetic nanoparticles / / Paolo Arosio, editor |
| Pubbl/distr/stampa | [Place of publication not identified] : , : MDPI - Multidisciplinary Digital Publishing Institute, , [2023] |
| Descrizione fisica | 1 online resource (276 pages) |
| Disciplina | 615.19 |
| Soggetto topico |
Nanoparticles
Magnetic nanoparticles |
| ISBN | 3-0365-6207-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | About the Editor -- Applications and Properties of Magnetic Nanoparticles -- Comparative Modeling of Frequency Mixing Measurements of Magnetic Nanoparticles Using Micromagnetic Simulations and Langevin Theory -- Highly Sensitive Fluorescent Detection of Acetylcholine Based on the Enhanced Peroxidase-Like Activity of Histidine Coated Magnetic Nanoparticles -- Boosting Magnetoelectric Effect in Polymer-Based Nanocomposites -- The Heating Efficiency and Imaging Performance of Magnesium Iron Oxide@tetramethyl Ammonium Hydroxide Nanoparticles for Biomedical Applications -- Evaluation of Physicochemical Properties of Amphiphilic 1,4-Dihydropyridines and Preparation of Magnetoliposomes -- Inactivation of Bacteria Using Bioactive Nanoparticles and Alternating Magnetic Fields -- Deviation of Trypsin Activity Using Peptide Conformational Imprints -- Determination of Cobalt Spin-Diffusion Length in Co/Cu Multilayered Heterojunction Nanocylinders Based on Valet-Fert Model -- Magnetic Imaging of Encapsulated Superparamagnetic Nanoparticles by Data Fusion of Magnetic Force Microscopy and Atomic Force Microscopy Signals for Correction of Topographic Crosstalk -- Coating Effect on the 1H-NMR Relaxation Properties of Iron Oxide Magnetic Nanoparticles -- Application of Magnetosomes in Magnetic Hyperthermia -- Room Temperature Magnetic Memory Effect in Cluster-Glassy Fe-Doped NiO Nanoparticles -- Magnetocrystalline and Surface Anisotropy in CoFe2O4 Nanoparticles -- Biocompatible Magnetic Fluids of Co-Doped Iron Oxide Nanoparticles with Tunable Magnetic Properties -- Influence of Experimental Parameters of a Continuous Flow Process on the Properties of Very Small Iron Oxide Nanoparticles (VSION) Designed for T1-Weighted Magnetic Resonance Imaging (MRI) -- Synthesis of Magnetic Ferrite Nanoparticles with High Hyperthermia Performance via a Controlled Co-Precipitation Method -- Magnetic Nanoparticles Functionalized Few-Mode-Fiber-Based Plasmonic Vector Magnetometer. |
| Record Nr. | UNINA-9910647232403321 |
| [Place of publication not identified] : , : MDPI - Multidisciplinary Digital Publishing Institute, , [2023] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Applications of targeted nano drugs and delivery systems : nanoscience and nanotechnology in drug delivery / / edited by Shyam S. Mohapatra, [and four others]
| Applications of targeted nano drugs and delivery systems : nanoscience and nanotechnology in drug delivery / / edited by Shyam S. Mohapatra, [and four others] |
| Pubbl/distr/stampa | Amsterdam, Netherlands : , : Elsevier, , 2019 |
| Descrizione fisica | 1 online resource (684 pages) |
| Disciplina | 615.19 |
| Collana | Micro & nano technologies series |
| Soggetto topico |
Nanoparticles
Nanomedicine |
| ISBN |
0-12-814030-5
0-12-814029-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910583319903321 |
| Amsterdam, Netherlands : , : Elsevier, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Le applicazioni della chimica farmaceutica / Camille Georges Wermuth
| Le applicazioni della chimica farmaceutica / Camille Georges Wermuth |
| Autore | Wermuth, Camille G. |
| Pubbl/distr/stampa | Napoli : EdiSES, c2000 |
| Descrizione fisica | xvii, 972 p. ; 25 cm |
| Disciplina | 615.19 |
| Soggetto topico | Pharmaceutical chemistry |
| ISBN | 8879591916 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ita |
| Record Nr. | UNISALENTO-991002380919707536 |
|
Wermuth, Camille G.
|
||
| Napoli : EdiSES, c2000 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. del Salento | ||
| ||
Applied biophysics for drug discovery / / edited by Donald Huddler, Edward R. Zartler
| Applied biophysics for drug discovery / / edited by Donald Huddler, Edward R. Zartler |
| Pubbl/distr/stampa | Hoboken, New Jersey ; ; Chichester, West Sussex, England : , : Wiley, , 2017 |
| Descrizione fisica | 1 online resource (292 pages) : illustrations, graphs |
| Disciplina | 615.19 |
| Soggetto topico |
Drug development
Drugs - Design Biophysics |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-119-09950-1
1-119-09949-8 1-119-09951-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910270886603321 |
| Hoboken, New Jersey ; ; Chichester, West Sussex, England : , : Wiley, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Applied biophysics for drug discovery / / edited by Donald Huddler, Edward R. Zartler
| Applied biophysics for drug discovery / / edited by Donald Huddler, Edward R. Zartler |
| Pubbl/distr/stampa | Hoboken, New Jersey ; ; Chichester, West Sussex, England : , : Wiley, , 2017 |
| Descrizione fisica | 1 online resource (292 pages) : illustrations, graphs |
| Disciplina | 615.19 |
| Soggetto topico |
Drug development
Drugs - Design Biophysics |
| ISBN |
1-119-09950-1
1-119-09949-8 1-119-09951-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910831078103321 |
| Hoboken, New Jersey ; ; Chichester, West Sussex, England : , : Wiley, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Applied pharmaceutical practice and nutraceuticals : Natural Product Developments / edited by Debarshi Kar Mahapatra, Cristóbal Noé Aguilar, A.K. Haghi
| Applied pharmaceutical practice and nutraceuticals : Natural Product Developments / edited by Debarshi Kar Mahapatra, Cristóbal Noé Aguilar, A.K. Haghi |
| Pubbl/distr/stampa | Palm Bay, FL, : Apple Academic Press, , 2021 |
| Disciplina | 615.19 |
| Soggetto non controllato |
Nutrizione - Farmacologia
Sostanze naturali - Uso terapeutico Nutraceutica |
| ISBN | 9781771889247 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910567000303321 |
| Palm Bay, FL, : Apple Academic Press, , 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Approaching Complex Diseases [[electronic resource] ] : Network-Based Pharmacology and Systems Approach in Bio-Medicine / / edited by Mariano Bizzarri
| Approaching Complex Diseases [[electronic resource] ] : Network-Based Pharmacology and Systems Approach in Bio-Medicine / / edited by Mariano Bizzarri |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (XVI, 483 p. 49 illus., 41 illus. in color.) |
| Disciplina | 615.19 |
| Collana | Human Perspectives in Health Sciences and Technology |
| Soggetto topico |
Pharmacology
Systems biology Oncology Medicine—Philosophy Pharmacology/Toxicology Systems Biology Oncology Philosophy of Medicine Farmacologia Ciències de la salut |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-32857-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1. Revisiting the concept of human disease (Mariano Bizzarri, Mirko Minini, and Noemi Monti) -- Chapter 2. Dynamical aspects of pharmacokinetic/pharmacodynamics and quantitative systems pharmacology models (Ioannis Loisios-Konstantinidis, Panteleimon D. Mavroudis, Panos Macheras) -- Chapter 3. The efficiency of multi-target drugs: a network approach (Lucas N. Alberca, Alan Talevi) -- Chapter 4. Mining Complex Biomedical Literature for Actionable Knowledge on Rare Diseases (Vinicius M. Alvesa, Stephen J. Capuzzia, Nancy Baker, Eugene N. Muratov, Alexander Trospsha, and Anthony J. Hickey) -- Chapter 5. Big Data, Personalized Medicine and Network Pharmacology: beyond the current paradigms (Alessandro Giuliani and Virginia Todde) -- Chapter 6. Epigenetic Control Using Small Molecules in Cancer (Tomohiro Kozako, Yukihiro Itoh, Shinichiro Honda, Takayoshi Suzuki) -- Chapter 7. Multiscale Modelling of Cancer: Micro-, Meso- and Macro-scales of Growth and Spread (Mark AJ Chaplain) -- Chapter 8. Precision Oncology vs Phenotypic approaches in the management of cancer: a case for the postmitotic state (Armando Aranda-Anzaldo and Myrna A.R. Dent) -- Chapter 9. Migrastatics - anti-metastatic drugs targeting cancer cell invasion (Aneta Gandalovičová , Daniel Rosel , Jan Brábek) -- Chapter 10. Critical steps in Epithelial-Mesenchymal transition as target for cancer treatment (Evgeny V. Denisov, Mohit Kumar Jolly, Vitaly P. Shubin, Alexey S. Tsukanov, Nadezhda V. Cherdyntseva) -- Chapter 11. Targeting the tumor-associated macrophages for ‘normalizing’ cancer (Julia Kzhyshkowska) -- Chapter 12. Tumor Reversion induced by embryo and oocyte extracts (Sara Proietti, Andrea Pensotti and Alessandra Cucina) -- Chapter 13. Trabectedin, a drug acting on both cancer cells and the tumor microenvironment (Paola Allavena, Manuela Liguori, Cristina Belgiovine) -- Chapter 14. Advances in Characterizing Recently-identified Molecular Actions of Melatonin: Clinical Implications (Russel J. Reiter, Ramaswamy Sharma, Sergio A. Rosales-Corral, Ana Coto-Montes, Jose Antonio Boga, Jerry Vriend) -- Chapter 15. Multitarget activities of Inositol and Inositol Hexakisphosphate (Ivana Vucenik) -- Chapter 16. Integration of Phytochemicals and Phytotherapy into Cancer Precision Medicine (Nadire Özenver and Thomas Efferth) -- Chapter 17. Synergistic Effects of Chinese Herbal Medicine and Biological Networks (Deep Jyoti Bhuyan, Saumya Perera1, Kirandeep Kaur, Muhammad A. Alsherbiny, Mitchell Low, Sai-Wang Seto, Chun-Guang Li, Xian Zhou) -- Chapter 18. Medicinal herbs: its therapeutic use in obstetrics and gynaecology (Irene Orbe, Daniel Paz, Leyre Pejenaute, Andrea Puente, Laura Diaz de Alda, Sandra Yague, Iñaki Lete) -- Chapter 19. Overcoming Antibiotic Resistance: New Perspectives (Matteo Bassetti, Elda Righi). |
| Record Nr. | UNINA-9910409698303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
