Stem cells : scientific facts and fiction / / edited by Christine L. Mummery, Anja van de Stolpe, Bernard Roelen, Hans Clevers

• Pubblicazione: London : , : Academic Press, , 2014; ©2014
• Edizione: 2nd edition.
• Descrizione fisica: 1 online resource (446 p.)
• Disciplina: 616.02774
• Soggetto topico: Stem cells - Research
• Persona (resp. second.): MummeryC. L <1953-, > (Christine L.); StolpeAnja van de <1956-, >; RoelenBernard A. J. <1968-, >; CleversHans
• Note generali: Includes index.
• Nota di contenuto: Front Cover; Stem Cells: Scientific Facts and Fiction; Copyright Page; Contents; Preface; Acknowledgements; 1 The Biology of the Cell; 1.1 Organisms' Composition; 1.2 Deoxyribonucleic Acid, Genes, and Chromosomes; 1.3 How the Amount of Messenger Ribonucleic Acid is Regulated; 1.4 From Messenger Ribonucleic Acid to a Functional Protein; 1.5 From Deoxyribonucleic Acid and Proteins to a Cell with a Specific Function; 1.5.1 Epigenetic Regulation; 1.5.2 Ribonucleic Acid Interference; 1.6 Deoxyribonucleic Acid Differences Between Genomes; 1.7 Diseases Due to Variations and Genome Mutations ; 1.8 Dominant or Recessive1.9 Deoxyribonucleic Acid Outside the Nucleus: Bacterial Remains; 1.10 Cell Lines and Cell Culture; 2 Embryonic Development; 2.1 Fertilization and Early Embryo Development; 2.2 Sex Cells and Germ Cell Tumors; 3 What Are Stem Cells?; 3.1 What are the Properties of Stem Cells That Make Them Different from Other Cells?; 3.2 Totipotency and Pluripotency, and Embryonic Stem Cells; 3.3 Multipotency, Unipotency, and Adult Stem Cells; 3.4 Cell Division and Aging: The Role of Telomerase; 3.5 The Relationship Between Cell Division and Differentiation: Epigenetics ; 3.6 Epigenetics in Stem Cells4 Of Mice and Men: The History of Embryonic Stem Cells; 4.1 How it All Began: Pluripotent Cells in Early Embryos; 4.2 Mouse Embryonal Carcinoma Cell Lines; 4.3 Pluripotent Cells in an Early Embryo; 4.4 Mouse Embryonic Stem Cell Lines; 4.5 Toward Human Embryonic Stem Cells; 4.6 On the Road to Stem Cell Therapy; 4.7 Biased Interpretation; 4.8 The Future: Stem Cell Transplantation as a Clinical Treatment; 4.9 Breakthrough of the Decade in the Twenty-First Century: Induced Pluripotent Stem Cells; 5 Origins and Types of Stem Cells: What's in a Name? ; 5.1 Pluripotent Stem Cells5.1.1 Embryonal Carcinoma Cells; 5.1.2 Embryonic Stem Cells; 5.1.3 Embryonic Germ Cells; 5.1.4 Spermatogonial Stem Cells; 5.1.5 Induced Pluripotent Stem Cells; 5.2 Multipotent Stem Cells; 5.2.1 Bone Marrow; 5.2.2 Umbilical Cord Blood; 6 Cloning: History and Current Applications; 6.1 Before Dolly; 6.2 Cloning Pets: Snuppy, Missy, and Copycat; 6.3 Just Imagine What Could Be; 6.4 Cloning Domestic Livestock; 6.5 Cloning Challenges; 7 Regenerative Medicine: Clinical Applications of Stem Cells; 7.1 Therapeutic Cell Transplantation ; 7.2 Number of Cells Needed for Cell Transplantation7.3 Why Some Diseases will be Treatable with Stem Cells in the Future and Others Not; 7.3.1 Loss of One Cell Type or More Cell Types; 7.3.2 Inherited and Acquired Diseases; 7.3.3 Diabetes Type 1: An Autoimmune Disease; 7.3.4 Spinal Cord Injury and Multiple Sclerosis: Restoring Demyelination; 7.3.5 Macular Degeneration: The Ideal Disease; 7.3.6 Deafness; 7.4 The Best Stem Cells for Transplantation; 7.5 Combining Gene Therapy with Stem Cell Transplantation; 7.6 Where to Transplant Stem Cells and Their Effect ; 7.7 Cell Types Available for Cell Transplantation
• Sommario/riassunto: The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cell
• Titolo autorizzato: Stem cells
• ISBN: 0-12-411567-5
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 996426338803316
• Lo trovi qui: Univ. di Salerno