The Role of PPARs in Disease

• Autore: Wagner Nicole
• Pubblicazione: Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022
• Descrizione fisica: 1 electronic resource (274 p.)
• Soggetto topico: Medicine; Physiology
• Soggetto non controllato: peroxisome-proliferator activated receptors; tumor angiogenesis; tumor progression; metastasis formation; endothelial cells; RNA sequencing; PPARs; toxicology; pharmacology; ligand; vascular; coronary artery; lipidomics; eicosanoids; inflammation; CYP450; peroxisome proliferator-activated receptor; angiogenesis; proliferation; metastasis; immortality; resistance to cell death; growth suppressors; immune system; cellular metabolism; PPAR; nuclear receptors; addiction; alcohol; nicotine; opioids; psychostimulants; animal models; human studies; Alzheimer’s; risk factors; PPARα; lipids; fatty acids; modulators; cognition; sex; therapy; hypertrophic adipocytes; PPARG isoforms; PPARG splicing; dominant-negative isoform; in vitro adipocytes; adipogenesis; hypertrophic obesity; insulin-resistance; peroxisome proliferator-activated receptors (PPARs); synthetic agonists; non-alcoholic fatty liver disease (NAFLD); non-alcoholic steatohepatitis (NASH); fibrosis; Sirtuin1; peroxisome proliferator-activated receptor-γ coactivator-1α; peroxisome proliferator activated receptors; obesity; metabolic syndrome; vitamin B12; folate; fetal programming; inherited metabolic disorders; PGC-1α, disease; kidney; cancer; AKI; CKD; nephron; PKD; cilia; cystogenesis; ligands; Alzheimer’s disease (AD)
• Persona (resp. second.): WagnerKay-Dietrich; WagnerNicole
• Sommario/riassunto: This reprint combines recent original manuscripts and reviews covering the multiple functions of peroxisome proliferator-activated receptors in physiology and pathophysiology. Potential applications and limitations of PPAR agonists and antagonists are discussed. All original contributions were published in Cells.
• Titolo autorizzato: The Role of PPARs in Disease
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910566482503321
• Lo trovi qui: Univ. Federico II