Immunohistochemical Expression

• Autore: Caltabiano Rosario
• Pubblicazione: Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021
• Descrizione fisica: 1 online resource (168 p.)
• Soggetto topico: Medicine
• Soggetto non controllato: ABCB5; c-kit; carcinogenesis; chaperonopathies; cytokeratin; DEN; differential diagnosis; EGCG; enteric nervous system; excretion fraction of uric acid; follicular adenoma; follicular carcinoma; heart; Hsp27; Hsp60; Hsp70; Hsp90; human embryonal/fetal tissues; hypouricemia; immunohistochemistry; inflammation; initial lymphatics; kidney; liver; macroH2A; matrix metalloproteinases; megacystis; metastasis; molecular chaperone; n/a; neoplastic tissue; NGAL; outcome and prognosis; oxidative stress; PDGFR; pericardium; prognosis; prognostic factor; prostate cancer; SLC22A12; temporomandibular joint; temporomandibular joint disorder; thyroid; training exercise; ultra-structural changes; URAT1; uric acid transporters; urinary tract malformations; uveal melanoma; VDR; Vitamin D; WT1
• Persona (resp. second.): LoretoCarla; CaltabianoRosario
• Sommario/riassunto: Immunohistochemistry (IHC) is an ancillary method, widely used in pathologists' practice, that allows identifying diagnostic and prognostic/predictive of therapeutic response protein markers on tissue samples by the use of specific monoclonal antibodies and chromogenic substances that guarantee the visualization of an antibody-antigene binding complex under a light microscope [1]. Coon et al., in 1941 [2], first introduced the use of fluorochrome-conjugated antibodies in clinical practice. Since then, IHC has gone from being a useful tool for identifying the differentiation line of otherwise undifferentiated cells to a technique capable of providing not only diagnostic but also prognostic and predictive indications of responses to specific therapeutic options [1,3]. The abovementioned peculiarities have made IHC one of the most used ancillary methods in the histopathological approach to human neoplastic and non-neoplastic diseases [3-5]. This Special Issue contains 11 accepted papers that provide readers with a comprehensive update on current and future applications of IHC in medical practice.
• Titolo autorizzato: Immunohistochemical Expression
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910557380403321
• Lo trovi qui: Univ. Federico II