NK Cell Subsets in Health and Disease: New Developments

• Autore: Emanuela Marcenaro
• Pubblicazione: Frontiers Media SA, 2017
• Descrizione fisica: 1 online resource (243 p.)
• Soggetto topico: Medicine and Nursing
• Soggetto non controllato: anti-tumor responses; anti-viral responses; ILCs; immune checkpoints; immunotherapy; inflammation; NK cell subsets
• Persona (resp. second.): Luigi D. Notarangelo; Jordan S. Orange; Eric Vivier
• Sommario/riassunto: Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.
• Altri titoli varianti: NK Cell Subsets in Health and Disease
• Titolo autorizzato: NK Cell Subsets in Health and Disease: New Developments
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910261136003321
• Lo trovi qui: Univ. Federico II