LEADER 02226nam 2200457z- 450 001 9910261136003321 005 20210211 035 $a(CKB)4100000002484732 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/54691 035 $a(oapen)doab54691 035 $a(EXLCZ)994100000002484732 100 $a20202102d2017 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aNK Cell Subsets in Health and Disease: New Developments 210 $cFrontiers Media SA$d2017 215 $a1 online resource (243 p.) 225 1 $aFrontiers Research Topics 311 08$a2-88945-350-2 330 $aNatural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology. 517 $aNK Cell Subsets in Health and Disease 606 $aMedicine and Nursing$2bicssc 610 $aanti-tumor responses 610 $aanti-viral responses 610 $aILCs 610 $aimmune checkpoints 610 $aimmunotherapy 610 $ainflammation 610 $aNK cell subsets 615 7$aMedicine and Nursing 700 $aEmanuela Marcenaro$4auth$01320421 702 $aLuigi D. Notarangelo$4auth 702 $aJordan S. Orange$4auth 702 $aEric Vivier$4auth 906 $aBOOK 912 $a9910261136003321 996 $aNK Cell Subsets in Health and Disease: New Developments$93034286 997 $aUNINA