Mitogen Activated Protein Kinases : Functions in Signal Transduction and Human Diseases

• Autore: Tikkanen Ritva
• Pubblicazione: Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020
• Descrizione fisica: 1 online resource (276 p.)
• Soggetto topico: Biology, life sciences; Research & information: general
• Soggetto non controllato: angiogenesis; antimicrobial peptide; aortic valve sclerosis; aortic valve stenosis; apoptosis; atherosclerosis; bone remodeling; bronchopulmonary dysplasia; cancer; cancer signaling; cecropin A; cell cycle; Compatibility; CR; cytokines; DAPK; DOK4; downregulation; DUSP1; ERK; ERK1/2; erlotinib; extracellular signal-regulated kinase 5 (ERK5); extracellular signal-regulated kinases 1/2; FGF-induced signaling; FR180204; FRS2; gastric ulcer; HPAECs; hyperoxia; infantile myofibromatosis; inflammation; JNK; JNKs; Kv4.2; MAPK; MAPK kinetics; MAPK/PI3K/Akt signaling pathway; MEK/ERK signaling; metabolic profiling; mitochondria; mitochondrial dysfunction; mitogen-activated protein kinase pathway (MAPK pathway); mitogen-activated protein kinases (MAPKs); MKK4; MKK7; N-heterocyclic carbene; n/a; naphthalimide-metal complex conjugates; neuro-inflammation; neurodegeneration; NF-κB; osteoclast differentiation; oxidative stress; p38; p38 MAPK; p38 MAPKs; p53; Parkinson's disease; PC12 cells; phosphorylation; platelet-derived growth factor receptor; porcine intestinal epithelial cell; protein kinase inhibitors; protein tyrosine phosphatase interacting protein 51 (PTPIP51); protein-protein interaction (PPI); psoriasis; PTPN6; Rabdosia inflexa; reactive oxygen species; receptor tyrosine kinases; ROS; SIRT1; SIRT2; SR; SRC; sunitinib; T2DM; targeted therapy; tight junction protein; U0126
• Persona (resp. second.): Nikolic-PatersonDavid; TikkanenRitva
• Sommario/riassunto: Mitogen-activated protein kinases (MAPK) are a large family of enzymes that function as signal transducers to regulate a diverse range of physiological responses. However, signaling via extracellular signal-regulated kinase (ERK), c-Jun amino terminal kinase (JNK), and p38 MAPK also underpin many disease processes. This Special Issue provides new insights into how MAPK signaling contributes to specific pathological processes across a range of conditions, including disorders of lung development, type 2 diabetes, proliferative skin diseases, cardiovascular diseases, and neurological diseases.
• Altri titoli varianti: Mitogen Activated Protein Kinases
• Titolo autorizzato: Mitogen Activated Protein Kinases
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910557405603321
• Lo trovi qui: Univ. Federico II