LEADER 04501nam 2201345z- 450 001 9910557405603321 005 20231214133454.0 035 $a(CKB)5400000000043620 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/68643 035 $a(EXLCZ)995400000000043620 100 $a20202105d2020 |y 0 101 0 $aeng 135 $aurmn|---annan 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMitogen Activated Protein Kinases$eFunctions in Signal Transduction and Human Diseases 210 $aBasel, Switzerland$cMDPI - Multidisciplinary Digital Publishing Institute$d2020 215 $a1 electronic resource (276 p.) 311 $a3-03928-070-8 311 $a3-03928-071-6 330 $aMitogen-activated protein kinases (MAPK) are a large family of enzymes that function as signal transducers to regulate a diverse range of physiological responses. However, signaling via extracellular signal-regulated kinase (ERK), c-Jun amino terminal kinase (JNK), and p38 MAPK also underpin many disease processes. This Special Issue provides new insights into how MAPK signaling contributes to specific pathological processes across a range of conditions, including disorders of lung development, type 2 diabetes, proliferative skin diseases, cardiovascular diseases, and neurological diseases. 517 $aMitogen Activated Protein Kinases 606 $aResearch & information: general$2bicssc 606 $aBiology, life sciences$2bicssc 610 $aRabdosia inflexa 610 $ainflammation 610 $agastric ulcer 610 $acytokines 610 $aMAPK 610 $aNF-?B 610 $aextracellular signal-regulated kinases 1/2 610 $ahyperoxia 610 $abronchopulmonary dysplasia 610 $aHPAECs 610 $aangiogenesis 610 $acell cycle 610 $aSIRT1 610 $aoxidative stress 610 $apsoriasis 610 $aantimicrobial peptide 610 $acecropin A 610 $atight junction protein 610 $aMEK/ERK signaling 610 $aporcine intestinal epithelial cell 610 $aextracellular signal-regulated kinase 5 (ERK5) 610 $aKv4.2 610 $aPC12 cells 610 $ainfantile myofibromatosis 610 $areceptor tyrosine kinases 610 $aplatelet-derived growth factor receptor 610 $aprotein kinase inhibitors 610 $asunitinib 610 $aerlotinib 610 $aFR180204 610 $aU0126 610 $atargeted therapy 610 $aapoptosis 610 $aERK1/2 610 $aJNKs 610 $amitochondrial dysfunction 610 $aneurodegeneration 610 $aneuro-inflammation 610 $ap38 MAPKs 610 $aParkinson's disease 610 $amitogen-activated protein kinases (MAPKs) 610 $aMAPK kinetics 610 $aosteoclast differentiation 610 $abone remodeling 610 $aDAPK 610 $aERK 610 $ap38 610 $aJNK 610 $amitogen-activated protein kinase pathway (MAPK pathway) 610 $aprotein tyrosine phosphatase interacting protein 51 (PTPIP51) 610 $aprotein-protein interaction (PPI) 610 $acancer signaling 610 $aSR 610 $aCR 610 $aCompatibility 610 $aT2DM 610 $ametabolic profiling 610 $aMAPK/PI3K/Akt signaling pathway 610 $areactive oxygen species 610 $aPTPN6 610 $aSRC 610 $aDOK4 610 $aMKK4 610 $aMKK7 610 $ap53 610 $aDUSP1 610 $aSIRT2 610 $aatherosclerosis 610 $aaortic valve sclerosis 610 $aaortic valve stenosis 610 $anaphthalimide-metal complex conjugates 610 $aN-heterocyclic carbene 610 $amitochondria 610 $aROS 610 $ap38 MAPK 610 $acancer 610 $aFGF-induced signaling 610 $aFRS2 610 $aphosphorylation 610 $adownregulation 615 7$aResearch & information: general 615 7$aBiology, life sciences 700 $aTikkanen$b Ritva$4edt$01299260 702 $aNikolic-Paterson$b David$4edt 702 $aTikkanen$b Ritva$4oth 702 $aNikolic-Paterson$b David$4oth 906 $aBOOK 912 $a9910557405603321 996 $aMitogen Activated Protein Kinases$93025089 997 $aUNINA