Biomimetic Radical Chemistry and Applications 2021

• Autore: Chatgilialoglu Chryssostomos
• Pubblicazione: Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022
• Descrizione fisica: 1 online resource (244 p.)
• Soggetto topico: Chemistry; Inorganic chemistry; Research & information: general
• Soggetto non controllato: [4Fe-4S] cluster; aggregation; antibiotics; biomimetic chemistry; bioorganometallic intermediate; catalase mimics; charge transfer; chemical nucleases; chemiluminescence; collagen; copper complexes; crosslink; cysteine; di-tryptophan; di-tyrosine; diiron-peroxo complexes; dimerization; disulfides; DNA; DNA biosensor; DNA hole transfer; DNA oxidation; DNA-drug interaction; electron transfer; EPR spectroscopy; free radicals; G-quadruplex; guanine; guanine radical cation; guanyl radical; hyaluronic acid; hydroxyl radical; inhibitors; IspH; keratoconus; ketone reduction; kinetic studies; kinetics; laser flash photolysis; light emission; LytB; mass spectrometry; MEP pathway; metallodrugs; methionine; molecular dynamics; n/a; neighboring group effect; oligonucleotides; one-electron oxidants; oxidation; peptides; peroxide; protein oxidation; proteins; proteomics; pulse radiolysis; quantum coherence; quantum dynamics; radicals; reaction mechanisms; reactive oxygen species; reactive oxygen species (ROS); reductive dehydroxylation; riboflavin; singlet oxygen; STEM; structure/activity; tautomerism; thiols; time-resolved spectroscopies; triplet state of carboxybenzophenone
• Persona (resp. second.): ChatgilialogluChryssostomos
• Sommario/riassunto: The high importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted considerable interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment, suitably designed to be a similar as possible to cellular conditions. This Special Issue provides readers with a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to be used as traces for the discoveries of some relevant biological processes. Several subjects are presented, with five articles and five reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications and bioinspired synthesis, with "free radicals" as the common denominator.
• Titolo autorizzato: Biomimetic Radical Chemistry and Applications 2021
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910576882903321
• Lo trovi qui: Univ. Federico II