New frontiers in asymmetric catalysis [[electronic resource] /] / edited by Koichi Mikami, Mark Lautens

• Pubblicazione: Hoboken, N.J., : Wiley-Interscience, c2007
• Descrizione fisica: 1 online resource (436 p.)
• Disciplina: 541.395; 541/.395
• Soggetto topico: Catalysis - Research; Asymmetry (Chemistry) - Research
• Altri autori: MikamiKoichi LautensM (Mark)
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: NEW FRONTIERS IN ASYMMETRIC CATALYSIS; CONTENTS; PREFACE; CONTRIBUTORS; 1 Ligand Design for Catalytic Asymmetric Reduction; 1.1 Introduction; 1.2 Hydrogenation of Olefins; 1.2.1 Enamide Hydrogenation with Rhodium Catalysts; 1.2.2 Hydrogenation of Functionalized Olefins with Ruthenium Catalysts; 1.2.3 Hydrogenation of Simple Olefins with Iridium Catalysts; 1.3 Reduction of Ketones; 1.3.1 Hydrogenation of Functionalized Ketones; 1.3.2 Hydrogenation of Simple Ketones; 1.3.3 Transfer Hydrogenation of Ketones; 1.3.4 Hydroboration of Ketones; 1.4 Reduction of Imines; References ; 2 Ligand Design for Oxidation2.1 Introduction; 2.2 Catalytic Enantioselective Epoxidation of Unfunctionalized Olefins; 2.3 Enantioselective Metal-Catalyzed Baeyer-Villiger Oxidation; 2.4 Optical Resolution during Oxidation of Alcohols; 2.5 Catalytic Enantioselective Oxidative Coupling of 2-Naphthols; 2.6 Concluding Remarks; References; 3 Ligand Design for C-C Bond Formation; 3.1 Introduction; 3.2 1,4-Addition and Related Reactions; 3.2.1 Copper Catalysis; 3.2.2 Rhodium Catalysis; 3.3 Cross-Coupling Reactions; 3.3.1 Kumada-Type Cross-Couplings; 3.3.2 Suzuki-Type Cross-Couplings; References ; 4 Activation of Small Molecules (C=O, HCN, RN=C, and CO(2))4.1 Introduction; 4.2 Asymmetric Hydroformylation of Olefins; 4.2.1 The Mechanism of Hydroformylation; 4.2.2 Scope and Limitation of Asymmetric Hydroformylation; 4.2.3 ''Greener'' Catalysts in Asymmetric Hydroformylation; 4.3 Asymmetric Hydrocarbohydroxylation and Related Reactions; 4.3.1 Asymmetric Hydrocarbalkoxylation of Alkenes; 4.3.2 Asymmetric Oxidative Hydrocarbalkoxylation of Alkenes; 4.3.3 Asymmetric Carbonylation of Carbon-Heteroatom Bonds; 4.4 Asymmetric Ketone Formation from Carbon-Carbon Multiple Bonds and CO ; 4.4.1 Asymmetric Pauson-Khand Reaction4.4.2 Asymmetric Alternating Copolymerization of Olefins with CO; 4.4.3 Asymmetric Polymerization of Isocyanide; 4.5 Asymmetric Hydrocyanation of Olefins; 4.6 Asymmetric Addition of Cyanide and Isocyanide to Aldehydes or Imines; 4.7 Asymmetric Addition of Carbon Dioxide; 4.8 Conclusion and Outlook; References; 5 Asymmetric Synthesis Based on Catalytic Activation of C-H Bonds and C-C Bonds; 5.1 Introduction; 5.2 Asymmetric Synthesis via Activation of C-H Bonds; 5.2.1 Formation of C-C Bonds; 5.2.2 Formation of C-O Bonds; 5.2.3 Formation of C-N Bonds ; 5.3 Asymmetric Synthesis via Activation of C-C Bonds5.3.1 Enantioselective C-C Bond Cleavage; 5.3.2 Formation of C-C Bonds; 5.3.3 Formation of C-O Bonds; 5.4 Conclusions and Outlook; Acknowledgments; References; 6 Recent Progress in the Metathesis Reaction; 6.1 Introduction; 6.2 Olefin Metathesis; 6.2.1 Ring-Closing Olefin Metathesis; 6.2.2 Cross-Metathesis (CM) of Diene; 6.2.3 Ring-Opening Metathesis (ROM)-Ring-Closing Metathesis (RCM) of Alkene; 6.2.4 Catalytic Asymmetric Olefin Metathesis; 6.3 Enyne Metathesis; 6.3.1 Ring-Closing Enyne Metathesis ; 6.3.2 Ring-Opening Metathesis (ROM)-Ring-Closing Metathesis (RCM) of Cycloalkene-Yne
• Sommario/riassunto: A compilation of recent advances and applications in asymmetric catalysisThe field of asymmetric catalysis has grown rapidly and plays a key role in drug discovery and pharmaceuticals. New Frontiers in Asymmetric Catalysis gives readers a fundamental understanding of the concepts and applications of asymmetric catalysis reactions and discusses the latest developments and findings. With contributions from preeminent scientists in their respective fields, it covers:* ""Rational"" ligand design, which is critically dependent on the reaction type (reduction, oxidation, and C-C bond
• Titolo autorizzato: New frontiers in asymmetric catalysis
• ISBN: 1-280-90102-0; 9786610901029; 0-470-09799-X; 0-470-09800-7
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910147019003321
• Lo trovi qui: Univ. Federico II