Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing

• Autore: Kim Jong Heon
• Pubblicazione: Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022
• Descrizione fisica: 1 online resource (282 p.)
• Soggetto topico: Biology, life sciences; Research & information: general
• Soggetto non controllato: 3-phenyl-1H-indazole; Acanthamoeba; Acanthamoeba keratitis; acetylsalicylic acid (ASA, aspirin); all-trans retinoic acid; anticandidal activity; antifungal; antifungal drugs; antifungals; Aspergillus spp; azole; azoles; beta-glucan; biological synthesis; candida; Candida; candida albicans; Candida auris; Candida spp; candidosis; canesten; CAP64; capsule; cell integrity; cell lysis; cell separation; cell wall; clotrimazole; Cryptococcus; cyst; cytokinesis; dermatophytes; drug; drug delivery systems; drug design; drug discovery; drug repurposing; drug targets; echinocandin drugs; echinocandin resistance; echinocandins; emerging fungi; Felis catus; fission yeast; Fks resistance hot spots; free-living ameba; fungi; Galleria mellonella model; host-directed drug therapy; hydrazones; indazole; invasive aspergillosis treatment; invasive fungal infections; isavuconazonium sulfate; Malassezia spp; marine; membrane potential (ΔΨM); microbiology; multidrug resistance; mycology; myconanotechnology; mycosis; n/a; nanoparticles; natural products; new targets; onychomycosis; photodynamic treatment; photosensitiser; polycations; polyenes; pyrazole; quinones; repositioning; resistance; retinoids; septation; sporotrichosis; synergy; therapeutic alternatives; ultrastructure; vaginal health; vaginitis; viral infections; vulvovaginal; yeast infection; yeasts; zoonoses; β(1,3)-D-glucan synthase
• Persona (resp. second.): ChengLuisa W; LandKirkwood; KimJong Heon
• Sommario/riassunto: This reprint describes recent advances made in the field of antifungal development, especially the discovery of new drugs and drug repurposing. The articles presented in this book provide useful information and insight for the development of new antifungal drugs or intervention strategies. The identification of new, safe molecules, and cellular targets, as well as the elucidation of their antifungal mechanisms of action, will further the effective control of fungal pathogens, especially those resistant to current therapeutic agents.
• Altri titoli varianti: Advances in Antifungal Development
• Titolo autorizzato: Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910585935503321
• Lo trovi qui: Univ. Federico II