04650nam 2201465z- 450 991058593550332120231214132947.0(CKB)5600000000483130(oapen)https://directory.doabooks.org/handle/20.500.12854/91208(EXLCZ)99560000000048313020202208d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierAdvances in Antifungal Development: Discovery of New Drugs and Drug RepurposingBaselMDPI - Multidisciplinary Digital Publishing Institute20221 electronic resource (282 p.)3-0365-4768-1 3-0365-4767-3 This reprint describes recent advances made in the field of antifungal development, especially the discovery of new drugs and drug repurposing. The articles presented in this book provide useful information and insight for the development of new antifungal drugs or intervention strategies. The identification of new, safe molecules, and cellular targets, as well as the elucidation of their antifungal mechanisms of action, will further the effective control of fungal pathogens, especially those resistant to current therapeutic agents.Advances in Antifungal DevelopmentResearch & information: generalbicsscBiology, life sciencesbicsscnanoparticlesfungidrug delivery systemsmarinebiological synthesismyconanotechnologycanestenclotrimazolevulvovaginalvaginitismycosiscandidosisyeast infectioncandidacandida albicansvaginal healthanticandidal activityindazolepyrazole3-phenyl-1H-indazoledrug designacetylsalicylic acid (ASA, aspirin)capsuleCAP64Cryptococcusmembrane potential (ΔΨM)photodynamic treatmentphotosensitiserultrastructuredrug repurposingantifungalsrepositioningyeastsemerging fungimultidrug resistancetherapeutic alternativesnew targetsCandida aurisAspergillus spp.antifungalbeta-glucanpolycationsGalleria mellonella modelretinoidsCandida spp.onychomycosisMalassezia spp.dermatophytesmicrobiologymycologyall-trans retinoic acidAcanthamoebafree-living amebaAcanthamoeba keratitisisavuconazonium sulfatecystdrugdrug discoverydrug targetsinvasive aspergillosis treatmentinvasive fungal infectionsfission yeastcell wallβ(1,3)-D-glucan synthaseantifungal drugsechinocandin drugsechinocandin resistanceFks resistance hot spotscytokinesisseptationcell separationcell integritycell lysissporotrichosisFelis catusquinoneshydrazoneszoonoseshost-directed drug therapyazolespolyenesechinocandinsviral infectionsazolesynergyresistanceCandidanatural productsResearch & information: generalBiology, life sciencesKim Jong Heonedt1318507Cheng Luisa WedtLand KirkwoodedtKim Jong HeonothCheng Luisa WothLand KirkwoodothBOOK9910585935503321Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing3033342UNINA