Mass spectrometry [[electronic resource] ] : principles and applications

• Autore: Hoffmann Edmond de
• Pubblicazione: Chichester, West Sussex, England ; ; Hoboken, N.J., : J. Wiley, c2007
• Edizione: 3rd ed. /
• Descrizione fisica: 1 online resource (503 p.)
• Disciplina: 543/.65
• Soggetto topico: Mass spectrometry
• Soggetto genere / forma: Electronic books.
• Altri autori: StroobantVincent
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Mass Spectrometry; Contents; Preface; Introduction; Principles; Diagram of a Mass Spectrometer; History; Ion Free Path; 1 Ion Sources; 1.1 Electron Ionization; 1.2 Chemical Ionization; 1.2.1 Proton Transfer; 1.2.2 Adduct Formation; 1.2.3 Charge-Transfer Chemical Ionization; 1.2.4 Reagent Gas; 1.2.5 Negative Ion Formation; 1.2.6 Desorption Chemical Ionization; 1.3 Field Ionization; 1.4 Fast Atom Bombardment and Liquid Secondary Ion Mass Spectrometry; 1.5 Field Desorption; 1.6 Plasma Desorption; 1.7 Laser Desorption; 1.8 Matrix-Assisted Laser Desorption Ionization; 1.8.1 Principle of MALDI ; 1.8.2 Practical Considerations1.8.3 Fragmentations; 1.8.4 Atmospheric Pressure Matrix-Assisted Laser Desorption Ionization; 1.9 Thermospray; 1.10 Atmospheric Pressure Ionization; 1.11 Electrospray; 1.11.1 Multiply Charged Ions; 1.11.2 Electrochemistry and Electric Field as Origins of Multiply Charged Ions; 1.11.3 Sensitivity to Concentration; 1.11.4 Limitation of Ion Current from the Source by the Electrochemical Process; 1.11.5 Practical Considerations; 1.12 Atmospheric Pressure Chemical Ionization; 1.13 Atmospheric Pressure Photoionization ; 1.14 Atmospheric Pressure Secondary Ion Mass Spectrometry1.14.1 Desorption Electrospray Ionization; 1.14.2 Direct Analysis in Real Time; 1.15 Inorganic Ionization Sources; 1.15.1 Thermal Ionization Source; 1.15.2 Spark Source; 1.15.3 Glow Discharge Source; 1.15.4 Inductively Coupled Plasma Source; 1.15.5 Practical Considerations; 1.16 Gas-Phase Ion-Molecule Reactions; 1.17 Formation and Fragmentation of Ions: Basic Rules; 1.17.1 Electron Ionization and Photoionization Under Vacuum; 1.17.2 Ionization at Low Pressure or at Atmospheric Pressure; 1.17.3 Proton Transfer; 1.17.4 Adduct Formation ; 1.17.5 Formation of Aggregates or Clusters1.17.6 Reactions at the Interface between Source and Analyser; 2 Mass Analysers; 2.1 Quadrupole Analysers; 2.1.1 Description; 2.1.2 Equations of Motion; 2.1.3 Ion Guide and Collision Cell; 2.1.4 Spectrometers with Several Quadrupoles in Tandem; 2.2 Ion Trap Analysers; 2.2.1 The 3D Ion Trap; 2.2.2 The 2D Ion Trap; 2.3 The Electrostatic Trap or 'Orbitrap'; 2.4 Time-of-Flight Analysers; 2.4.1 Linear Time-of-Flight Mass Spectrometer; 2.4.2 Delayed Pulsed Extraction; 2.4.3 Reflectrons; 2.4.4 Tandem Mass Spectrometry with Time-of-Flight Analyser ; 2.4.5 Orthogonal Acceleration Time-of-Flight Instruments2.5 Magnetic and Electromagnetic Analysers; 2.5.1 Action of the Magnetic Field; 2.5.2 Electrostatic Field; 2.5.3 Dispersion and Resolution; 2.5.4 Practical Considerations; 2.5.5 Tandem Mass Spectrometry in Electromagnetic Analysers; 2.6 Ion Cyclotron Resonance and Fourier Transform Mass Spectrometry; 2.6.1 General Principle; 2.6.2 Ion Cyclotron Resonance; 2.6.3 Fourier Transform Mass Spectrometry; 2.6.4 MS n in ICR/FTMS Instruments; 2.7 Hybrid Instruments; 2.7.1 Electromagnetic Analysers Coupled to Quadrupoles or Ion Trap ; 2.7.2 Ion Trap Analyser Combined with Time-of-Flight or Ion Cyclotron Resonance
• Sommario/riassunto: The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analysers and detectors. Tandem mass spectrometry is introduced early on and then developed in more detail in a later chapter. Emphasis is placed throughout the text on optimal utilisation conditions. Various fragmentation patterns are described together with analytical information that derives
• Titolo autorizzato: Mass spectrometry
• ISBN: 1-118-68194-0; 1-281-13527-5; 9786611135270; 0-470-03310-X; 0-470-51213-X
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910451252603321
• Lo trovi qui: Univ. Federico II