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Record Nr. |
UNINA9910451252603321 |
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Autore |
Hoffmann Edmond de |
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Titolo |
Mass spectrometry [[electronic resource] ] : principles and applications |
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Pubbl/distr/stampa |
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Chichester, West Sussex, England ; ; Hoboken, N.J., : J. Wiley, c2007 |
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ISBN |
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1-118-68194-0 |
1-281-13527-5 |
9786611135270 |
0-470-03310-X |
0-470-51213-X |
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Edizione |
[3rd ed. /] |
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Descrizione fisica |
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1 online resource (503 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Mass spectrometry |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Mass Spectrometry; Contents; Preface; Introduction; Principles; Diagram of a Mass Spectrometer; History; Ion Free Path; 1 Ion Sources; 1.1 Electron Ionization; 1.2 Chemical Ionization; 1.2.1 Proton Transfer; 1.2.2 Adduct Formation; 1.2.3 Charge-Transfer Chemical Ionization; 1.2.4 Reagent Gas; 1.2.5 Negative Ion Formation; 1.2.6 Desorption Chemical Ionization; 1.3 Field Ionization; 1.4 Fast Atom Bombardment and Liquid Secondary Ion Mass Spectrometry; 1.5 Field Desorption; 1.6 Plasma Desorption; 1.7 Laser Desorption; 1.8 Matrix-Assisted Laser Desorption Ionization; 1.8.1 Principle of MALDI |
1.8.2 Practical Considerations1.8.3 Fragmentations; 1.8.4 Atmospheric Pressure Matrix-Assisted Laser Desorption Ionization; 1.9 Thermospray; 1.10 Atmospheric Pressure Ionization; 1.11 Electrospray; 1.11.1 Multiply Charged Ions; 1.11.2 Electrochemistry and Electric Field as Origins of Multiply Charged Ions; 1.11.3 Sensitivity to Concentration; 1.11.4 Limitation of Ion Current from the Source by the Electrochemical Process; 1.11.5 Practical Considerations; 1.12 Atmospheric Pressure Chemical Ionization; 1.13 Atmospheric Pressure Photoionization |
1.14 Atmospheric Pressure Secondary Ion Mass Spectrometry1.14.1 Desorption Electrospray Ionization; 1.14.2 Direct Analysis in Real Time; |
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1.15 Inorganic Ionization Sources; 1.15.1 Thermal Ionization Source; 1.15.2 Spark Source; 1.15.3 Glow Discharge Source; 1.15.4 Inductively Coupled Plasma Source; 1.15.5 Practical Considerations; 1.16 Gas-Phase Ion-Molecule Reactions; 1.17 Formation and Fragmentation of Ions: Basic Rules; 1.17.1 Electron Ionization and Photoionization Under Vacuum; 1.17.2 Ionization at Low Pressure or at Atmospheric Pressure; 1.17.3 Proton Transfer; 1.17.4 Adduct Formation |
1.17.5 Formation of Aggregates or Clusters1.17.6 Reactions at the Interface between Source and Analyser; 2 Mass Analysers; 2.1 Quadrupole Analysers; 2.1.1 Description; 2.1.2 Equations of Motion; 2.1.3 Ion Guide and Collision Cell; 2.1.4 Spectrometers with Several Quadrupoles in Tandem; 2.2 Ion Trap Analysers; 2.2.1 The 3D Ion Trap; 2.2.2 The 2D Ion Trap; 2.3 The Electrostatic Trap or 'Orbitrap'; 2.4 Time-of-Flight Analysers; 2.4.1 Linear Time-of-Flight Mass Spectrometer; 2.4.2 Delayed Pulsed Extraction; 2.4.3 Reflectrons; 2.4.4 Tandem Mass Spectrometry with Time-of-Flight Analyser |
2.4.5 Orthogonal Acceleration Time-of-Flight Instruments2.5 Magnetic and Electromagnetic Analysers; 2.5.1 Action of the Magnetic Field; 2.5.2 Electrostatic Field; 2.5.3 Dispersion and Resolution; 2.5.4 Practical Considerations; 2.5.5 Tandem Mass Spectrometry in Electromagnetic Analysers; 2.6 Ion Cyclotron Resonance and Fourier Transform Mass Spectrometry; 2.6.1 General Principle; 2.6.2 Ion Cyclotron Resonance; 2.6.3 Fourier Transform Mass Spectrometry; 2.6.4 MS n in ICR/FTMS Instruments; 2.7 Hybrid Instruments; 2.7.1 Electromagnetic Analysers Coupled to Quadrupoles or Ion Trap |
2.7.2 Ion Trap Analyser Combined with Time-of-Flight or Ion Cyclotron Resonance |
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Sommario/riassunto |
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The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analysers and detectors. Tandem mass spectrometry is introduced early on and then developed in more detail in a later chapter. Emphasis is placed throughout the text on optimal utilisation conditions. Various fragmentation patterns are described together with analytical information that derives |
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