Introduction to Pharmaceutical Chemical Analysis
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| Autore: |
Hansen Steen
|
| Titolo: |
Introduction to Pharmaceutical Chemical Analysis
|
| Pubblicazione: | Hoboken, : Wiley, 2011 |
| Descrizione fisica: | 1 online resource (512 p.) |
| Disciplina: | 615.19 |
| Soggetto topico: | Drugs - Analysis |
| Pharmaceutical chemistry | |
| Altri autori: |
Pedersen-BjergaardStig
RasmussenKnut
|
| Note generali: | Description based upon print version of record. |
| Nota di contenuto: | Introduction to Pharmaceutical Chemical Analysis; Table of Contents; Preface; 1 Introduction to Pharmaceutical Analysis; 1.1 Applications and Definitions; 1.2 The Life of Medicines; 1.3 The Quality of Medical Products; 1.4 Summary; 2 International Pharmacopoeias, Regulations and Guidelines; 2.1 Overview of Legislation; 2.2 Legislation and Regulations for Industrial Production; 2.3 Life Time of Drugs and Drug Substances; 2.4 Pharmacopoeias; 2.5 International Harmonization; 2.5.1 International Conference on Harmonization; 2.5.2 Pharmacopoeial Discussion Group |
| 2.6 Legislation and Regulations for Pharmacy Production2.7 Summary; 3 Fundamental Chemical Properties, Buffers and pH; 3.1 pH and pKa; 3.2 Partition; 3.3 Stereochemistry; 3.4 Stability Testing; 3.5 Summary; 4 Fundamentals of Pharmaceutical Analysis; 4.1 What is a Pharmaceutical (Chemical) Analysis?; 4.2 How to Specify Quantities and Concentrations?; 4.3 Basic Laboratory Equipment; 4.3.1 The Analytical Balance; 4.3.2 Pipettes; 4.3.3 Volumetric Flasks; 4.3.4 Burettes; 4.4 How to Make Solutions and Dilutions; 4.5 Calibration of Analytical Methods; 4.6 Errors, Accuracy, and Precision | |
| 4.6.1 Systematic and Random Errors4.6.2 Accuracy and Precision; 4.7 Statistics; 4.7.1 Mean Value and Standard Deviation; 4.7.2 Confidence Intervals; 4.7.3 Comparison of Means with a t-Test; 4.7.4 Q-Test to Reject Outliers; 4.7.5 Linear Regression with the Method of Least Squares; 4.7.6 How to Present an Analytical Result; 4.8 Some Words and Concepts; 4.8.1 Analysis and Determination; 4.8.2 Sample Replicates and Measuring Replicates; 4.8.3 Interference; 4.8.4 Blind Samples; 5 Titrimetric Methods; 5.1 Introduction; 5.2 Acid-Base Titrations; 5.3 Acid-Base Titrations in Non-Aqueous Media | |
| 5.4 Redox Titrations5.5 Other Principles of Titration; 5.6 Summary; 6 Introduction to Spectroscopic Methods; 6.1 Electromagnetic Radiation; 6.2 Molecules and Electromagnetic Radiation; 6.3 Atoms and Electromagnetic Radiation; 6.4 Summary; 7 UV Spectrophotometry; 7.1 Principle of Quantitative Determination; 7.2 Principle of Identification; 7.3 Which Substances Have Strong UV Absorbance?; 7.4 Instrumentation; 7.5 Practical Work and Method Development; 7.6 Areas of Usage and Performance; 7.7 System Testing; 7.8 Summary; 8 IR Spectrophotometry; 8.1 IR Spectrophotometry; 8.2 Instrumentation | |
| 8.3 Scope8.4 Instrument Calibration; 8.5 NIR Spectrophotometry; 8.6 Applications; 8.7 Summary; 9 Atomic Spectrometry; 9.1 Atomic Absorption Spectrometry; 9.2 Instrumentation; 9.3 Applications and Performance; 9.4 Practical Work and Method Development; 9.5 Atomic Emission Spectrometry; 9.6 Instrumentation; 9.7 Summary; 10 Chromatography; 10.1 General Principles; 10.2 Retention; 10.3 Column Efficiency; 10.4 Selectivity; 10.5 Peak Symmetry; 10.6 Resolution; 10.7 Chromatographic Techniques; 10.8 Summary; 11 Chromatographic Separation Principles; 11.1 General Introduction | |
| 11.2 Normal Phase Chromatography | |
| Sommario/riassunto: | This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide. In addition, this textbook teaches the fundamentals of all the major analytical techniques used in the pharmaceutical laboratory, and teaches the international pharmacopoeias and guidelines of importance for the field. It is primarily intended for the pharmacy student, to teach the requirements in "analytical chemistry" for the 5 years pharmacy |
| Titolo autorizzato: | Introduction to Pharmaceutical Chemical Analysis |
| ISBN: | 1-283-30679-4 |
| 9786613306791 | |
| 1-119-95364-2 | |
| 1-119-95360-X | |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910139569303321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |