Immunotherapy, Tumor Microenvironment and Survival Signaling

• Autore: Golubovskaya Vita
• Pubblicazione: Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022
• Descrizione fisica: 1 online resource (376 p.)
• Soggetto topico: Clinical and internal medicine; Medicine and Nursing
• Soggetto non controllato: angiogenesis; antigen loss; Autophagy; BCMA; breast cancer; cancer; cancer immunotherapy; cancer metabolism; cancer nanomedicine; cancer stem cells; cancer vaccines; CAR macrophage; CAR T cell; CAR-T; CAR-T cells; cardiotoxicity; CD11; CD18; CD19; CD37; cell therapy; cell-cell contact; check point inhibitors; checkpoint; chemotherapy; chimeric antigen receptor; chimeric antigen receptors; clonogenicity; colorectal cancer; combination therapy; crosstalk; DCLK1; dendritic cells; electroporation; hypoxia; immune checkpoint inhibitor; immune checkpoint inhibitors; immune escape; immunogenic cell death; immunometabolism; immunomodulation; immunomodulators; immunotherapeutic agent; immunotherapies; immunotherapy; lentiviral transduction; lentivirus; leukemia cells; lung metastasis; lymphoma; lytic peptides; macrophages; melanoma; microenvironment; miRNA; mitochondria; mitochondrial transfer; myeloid-derived suppressor cells; n/a; nanoparticles; oncolytic viral therapy; pathogenesis; pediatric solid tumors; personalized medicine; programmed cell death 1 ligand 1; programmed cell death protein 1; regulatory T cells; resistance; risk factors; solid tumors; targeted therapy; targeted treatment; triple-negative breast cancer; tuft cells; tumor; tumor antigen; tumor antigens; tumor immune evasion; tumor microenvironment; tumor stem cells; tumor stroma; tunneling nanotubes; tyrosine kinase inhibitors; β2 integrins
• Persona (resp. second.): GolubovskayaVita
• Sommario/riassunto: The book is based on the Cancers journal Special Issue entitled "Immunotherapy, Tumor Microenvironment and Survival Signaling", and focuses on important problems concerning tumors and tumor microenvironment interactions, as well as novel immunotherapies such as CAR-T cell therapy. Immunotherapies have recently shown remarkable results in the treatment of cancer patients. However, there are still many questions that remain to be solved in regards to more effective therapies, such as the tumor heterogeneous profile, tumor microenvironment, and tumor survival epigenetic and genetic pathways, all of which make patients resistant to the presently available treatments for cancer. This book demonstrates different approaches to overcome the challenges faced by immunotherapies due to suppressive tumor microenvironments. This book includes 18 papers that can be divided into three chapters: 1. novel immunotherapies; 2. targeting tumor microenvironment and novel approaches; 3. targeting tumors and tumor microenvironment in different types of cancer.
• Titolo autorizzato: Immunotherapy, Tumor Microenvironment and Survival Signaling
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910580205403321
• Lo trovi qui: Univ. Federico II