Autore	Peter Isabelle S.
Pubbl/distr/stampa	London, England : , : Elsevier : , : AP, , 2015
Descrizione fisica	1 online resource (461 p.)
Disciplina	572.86
Soggetto topico	Genomics Genes Embryology
ISBN	0-12-404746-7
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Front Cover; IFC; GENOMIC CONTROL PROCESS; Copyright; About the Authors; Contents; Preface; Dedications; Chapter 1 - The Genome in Development; 1. Views of Development; 2. Levels of Control of Gene Expression: Transcriptional Regulation; 3. Levels of Control of Gene Expression: Noncoding RNAs; 4. Levels of Control of Gene Expression: Histone Modifications; 5. The Regulatory Genome; REFERENCES; Chapter 2 - Gene Regulatory Networks; 1. Introductory Overview of Developmental GRNs; 2. Boolean Spatial Output; 3. Regulatory States; 4. Regulation in Cis; 5. Module Choice; 6. Transcriptional Dynamics 7. Historical Origins and Antecedents of GRN TheoryREFERENCES; Chapter 3 - Genomic Strategies for Embryonic Development; 1. Common Principles of Embryonic Development; 2. Phylogenetic Framework; 3. Genomic Strategies of Control in Mode 1 Embryonic Processes; 4. Genomic Strategies of Control in Mode 2 Embryonic Processes; 5. Global Aspects of A/P Spatial Regulatory Patterning in the Syncytial Drosophila Blastoderm; REFERENCES; Chapter 4 - Genomic Control Processes in Adult Body Part Formation; 1. Common Principles of Body Part Formation; 2. Limbs in Amniotes; 3. Fly Legs 4. Establishment of Spatial Regulatory States in Early Development of Fly and Mammalian Brains5. The Vertebrate Heart; 6. Spatial Regulatory State Subdivision in and Around the Drosophila Ocellus; 7. The Vertebrate Gut; Chapter 5 - Genomic Strategies for Terminal Cell Fate Specification; 1. Circumstances of Terminal Cell Fate Specification; 2. Combinatorial Cis-Regulatory Definition of Differentiation Gene Batteries; 3. Cell Type Specification in Multipotential Embryonic Precursors; 4. A Comment on Stem Cells in Postembryonic Life 5. Modular Call-Up of Given Specification Processes in Multiple Developmental ContextsREFERENCES; Chapter 6 - On the Modeling of Developmental Gene Regulatory Networks; 1. Topological Network Models; 2. ODE Models of Circuit Dynamics; 3. Boolean Models of Network Logic; 4. Conclusions; REFERENCES; Chapter 7 - Evolution of Bilaterian Animals: Processes of Change and Stasis in Hierarchical Developmental Gene Regulatory Networks; 1. Introduction: Evolution by Genomic Change at Different Levels of GRN Hierarchy; 2. Evolution of the Body Plan by Co-Optive Alteration of GRN Structure 3. GRN Stasis and Phylogeny4. Trans-Phyletic Conservation of Cell Type-Specific Regulatory States; 5. Bilaterian Evolution; REFERENCES; Gene Index; Subject Index
Record Nr.	UNINA-9910792476203321

Autore	Engel Eric, Dr.
Pubbl/distr/stampa	New York, : Wiley-Liss, c2002
Descrizione fisica	1 online resource (303 p.)
Disciplina	572.86 616/.042
Altri autori (Persone)	AntonarakisStylianos E
Soggetto topico	Genetic disorders Genomic imprinting
Soggetto genere / forma	Electronic books.
ISBN	1-280-36634-6 9786610366347 0-470-24216-7 0-471-45913-5 0-471-22193-7
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Genomic Imprinting and Uniparental Disomy in Medicine; Contents; Foreword; Preface; Acknowledgments; Chapter 1 Introduction; Chapter 2 Detection of Uniparental Disomy and Imprinting by DNA Analysis; Chapter 3 Mechanisms Generating Uniparently Disomy and Genomic Imprinting Disorders; Chapter 4 Uniparental Disomy for Individual Human Chromosomes: Review of Cases; Chapter 5 ''Old'' and ''New'' Syndromes with Uniparental Disomy; Chapter 6 The Prader-(Labhardt)-Willi Syndrome; Chapter 7 The Angelman Syndrome (AS); Chapter 8 The Beckwith-Wiedemann Syndrome (BWS) Chapter 9 Genetic Counseling and Prenatal DiagnosisChapter 10 Genomic Imprinting in the Mouse; Chapter 11 Epilogue of an Unfinished Story; Index
Record Nr.	UNINA-9910142504803321

Pubbl/distr/stampa	London, United Kingdom : , : Academic Press, an imprint of Elsevier, , [2018]
Descrizione fisica	1 online resource (206 pages)
Disciplina	572.86
Soggetto topico	Genomics Genomics - Economic aspects Medical genetics
ISBN	0-12-811551-3 0-12-811531-9
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Record Nr.	UNINA-9910583317203321

Autore	Cantor Charles R. <1942->
Pubbl/distr/stampa	New York, : John Wiley & Sons, c1999
Descrizione fisica	1 online resource (621 p.)
Disciplina	572.8/6 572.86
Altri autori (Persone)	SmithCassandra
Collana	Baker Lecture Series
Soggetto topico	DNA - Analysis Nucleotide sequence Gene mapping
Soggetto genere / forma	Electronic books.
ISBN	1-280-36704-0 9786610367047 0-470-32291-8 0-471-46186-5 0-471-22056-6
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Contents; Preface; Introduction; 1 DNA Chemistry and Biology; Basic Properties of DNA; Covalent Structure; Double Helical Structure; Methylated Bases; Plasticity in DNA Structure; DNA Synthesis; DNA as a Flexible Set of Chemical Reagents; Basic DNA Biology; Genome Sizes; Number of Genes; Sources and Additional Readings; 2 A Genome Overview at the Level of Chromosomes; Basic Properties of Chromosomes; Bacterial Chromosomes; Chromosomes of Eukaryotic Organisms; Centromeres; Telomeres; Dynamic Behavior of Telomeres; Chromatin and the Higher-Order Structure of Chromosomes Chromosomes in the Cell CycleGenome Organization; Chromosome Purification; Chromosome Number; Unusual Characteristics of Sex Chromosomes and Mitochondria; Synteny; Sources and Additional Readings; 3 Analysis of DNA Sequences by Hybridization; Basic Requirements for Selectivity and Sensitivity; Detection of Specific DNA Sequences; Equilibria between DNA Double and Single Strands; Thermodynamics of the Melting of Short Duplexes; Thermodynamics of Imperfectly Paired Duplexes; Kinetics of the Melting of Short Duplexes; Kinetics of Melting of Long DNA; Kinetics of Double-Strand Formation ComplexityHybridization on Filters; Sensitive Detection; Sources and Additional Readings; 4 Polymerase Chain Reaction and Other Methods for In Vitro DNA Amplification; Why Amplify DNA?; Basic Principles of the Polymerase Chain Reaction (PCR); Noise in PCR: Contamination; PCR Noise: Mispriming; Misincorporation; Long PCR; Incorporating Extra Functionalities; Single-Sided PCR; Reducing Complexity with PCR; Additional Variants of the Basic PCR Reaction; Total Genome Amplification Methods; Application of PCR to Detect Molecules Other Than DNA DNA Amplification without Thermal Cycling and Other Alternatives to PCRFuture of PCR; Sources and Additional Readings; 5 Principles of DNA Electrophoresis; Physical Fractionation of DNA; Separation of DNA in the Ultracentrifuge; Electrophoretic Size Separations of DNA; Electrophoresis without Gels; Motions of DNA Molecules in Gels; Complex Effects of Gel Structure and Behavior; Biased Reptation Model of DNA Behavior in Gels; Pulsed Field Gel Electrophoresis (PFG); Macroscopic Behavior of DNA in PFG; Inadequacy of Reptation Models for PFG; DNA Trapping Electrophoresis Secondary Pulsed Field Gel Electrophoresis (SPFG)Entry of DNAs into Gels; Sources and Additional Readings; 6 Genetic Analysis; Why We Need Genetics; Basic Strategy for Genetic Analysis in the Human: Linkage Mapping; A Glossary of Genetic Terms; Relationship between the Physical and the Genetic Maps; Power of Mouse Genetics; Weakness of Human Genetics; Linkage Analysis Ignoring Recombination; Linkage Analysis with Recombination; Interval Mapping; Finding Genes by Genetic Mapping; Moving from Weak Linkage Closer to a Gene; Linkage Disequilibrium Complications in Linkage Disequilibrium and Genetic Maps in General
Record Nr.	UNINA-9910143509103321

Autore	HONGLADAROM, Soraj
Pubbl/distr/stampa	Hershey ; New York : Medical Information Science Reference, 2011
Descrizione fisica	XXII, 307 p. ; 29 cm
Disciplina	572.86
Collana	Premier reference source
Soggetto topico	Genoma
ISBN	978-1-61692-883-4
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Record Nr.	UNISA-990003557440203316