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Cell adhesion and human disease [[electronic resource] /] / [editors, Joan Marsh and Jamie A. Goode]



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Titolo: Cell adhesion and human disease [[electronic resource] /] / [editors, Joan Marsh and Jamie A. Goode] Visualizza cluster
Pubblicazione: Chichester ; ; New York, : Wiley, 1995
Descrizione fisica: 1 online resource (256 p.)
Disciplina: 611.01815
616.07
Soggetto topico: Cell adhesion
Cell adhesion molecules
Physiology, Pathological
Altri autori: MarshJoan  
GoodeJamie  
Note generali: "Ciba Foundation"--Cover.
"Symposium on Cell adhesion and human disease, held at the Ciba Foundation, London 17-19 May 1994"--P. v.
Nota di bibliografia: Includes bibliographical references and indexes.
Nota di contenuto: CELL ADHESION AND HUMAN DISEASE; Contents; Participants; Chairman's introduction; P-selectin knockout: a mouse model for various human diseases; Creation and characterization of E-selectin- and VCAM-1 -deficient mice; Von Willebrand's disease and the mechanisms of platelet function; Leukocyte adhesion deficiency (LAD) II; Leukocyte and endothelial adhesion molecules in ischaemialreperfusion injuries; General discussion I; The integrin (VLA-4) as a therapeutic target; Adhesion molecules in cutaneous inflammation; Defective cell-cell adhesion in the epidermis
E-cadherin as an invasion suppressorThe role of CD44 splice variants in human metastatic cancer; Early metastasis of human solid tumours: expression of cell adhesion molecules; General discussion I I; Mechanisms fibronectin b i m p I icat ions of VCAM-1 and nding to or integr rational drug design integrin CY& : n function and; General d iscussio n II; Treatment of inflammatory diseases with a monoclonal antibody to intercellular adhesion molecule 1; Identification of endogenous protein-associated carbohydrate ligands for E-selectin; Final discussion; Index of contributors; Subject index
Sommario/riassunto: Experts in their respective fields present papers concerned with the range of human diseases caused by defective or abnormal functioning of cell adhesion molecules. Discusses new therapeutic approaches to these maladies.
Titolo autorizzato: Cell adhesion and human disease  Visualizza cluster
ISBN: 1-282-12245-2
9786612122453
0-470-51471-X
0-470-51472-8
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910840569103321
Lo trovi qui: Univ. Federico II
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Serie: Ciba Foundation symposium ; ; 189.