03341nam 2200649 a 450 991084056910332120230421044507.01-282-12245-297866121224530-470-51471-X0-470-51472-8(CKB)1000000000376019(EBL)470580(SSID)ssj0000357652(PQKBManifestationID)11263413(PQKBTitleCode)TC0000357652(PQKBWorkID)10354083(PQKB)11299418(MiAaPQ)EBC470580(OCoLC)181178218(EXLCZ)99100000000037601919940927d1995 uy 0engur|n|---|||||txtccrCell adhesion and human disease[electronic resource] /[editors, Joan Marsh and Jamie A. Goode]Chichester ;New York Wiley19951 online resource (256 p.)Ciba Foundation symposium ;189"Ciba Foundation"--Cover."Symposium on Cell adhesion and human disease, held at the Ciba Foundation, London 17-19 May 1994"--P. v.0-471-95279-6 Includes bibliographical references and indexes.CELL ADHESION AND HUMAN DISEASE; Contents; Participants; Chairman's introduction; P-selectin knockout: a mouse model for various human diseases; Creation and characterization of E-selectin- and VCAM-1 -deficient mice; Von Willebrand's disease and the mechanisms of platelet function; Leukocyte adhesion deficiency (LAD) II; Leukocyte and endothelial adhesion molecules in ischaemialreperfusion injuries; General discussion I; The integrin (VLA-4) as a therapeutic target; Adhesion molecules in cutaneous inflammation; Defective cell-cell adhesion in the epidermisE-cadherin as an invasion suppressorThe role of CD44 splice variants in human metastatic cancer; Early metastasis of human solid tumours: expression of cell adhesion molecules; General discussion I I; Mechanisms fibronectin b i m p I icat ions of VCAM-1 and nding to or integr rational drug design integrin CY& : n function and; General d iscussio n II; Treatment of inflammatory diseases with a monoclonal antibody to intercellular adhesion molecule 1; Identification of endogenous protein-associated carbohydrate ligands for E-selectin; Final discussion; Index of contributors; Subject indexExperts in their respective fields present papers concerned with the range of human diseases caused by defective or abnormal functioning of cell adhesion molecules. Discusses new therapeutic approaches to these maladies.Ciba Foundation symposium ;189.Cell adhesionCongressesCell adhesion moleculesCongressesPhysiology, PathologicalCongressesCell adhesionCell adhesion moleculesPhysiology, Pathological611.01815616.07Marsh Joan91633Goode Jamie283336Ciba Foundation.MiAaPQMiAaPQMiAaPQBOOK9910840569103321Cell adhesion and human disease4136423UNINA