The assignment of the absolute configuration by NMR using chiral derivatizing agents : a practical guide / / J.M. Seco, Emilio Quiñoá, and R. Riguera

• Autore: Seco J. M (José Manuel)
• Pubblicazione: New York, New York : , : Oxford University Press, , 2015; ©2015
• Descrizione fisica: 1 online resource (265 p.)
• Disciplina: 543/.66
• Soggetto topico: Nuclear magnetic resonance spectroscopy; Spectrum analysis
• Persona (resp. second.): QuiñoáE (Emilio); RigueraR (Ricardo)
• Note generali: Previously issued in print: 2015.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: ""Cover""; ""The Assignment of the Absolute Configuration by NMR Using Chiral Derivatizing Agents""; ""Copyright""; ""Contents""; ""Preface""; ""Introduction""; ""1 The Theoretical Basis for Assignment by NMR""; ""1.1. Distinguishing Enantiomers by NMR: The Use of CDAs""; ""1.2. Structural Characteristics of the Auxiliaries and the Substrates""; ""1.3. Importance of the Conformation""; ""1.4. Importance of the Aromatic Shielding Effect""; ""1.5. Use of 13C NMR for Assignment""; ""1.6. Simplified Approaches to Assignment by NMR"" ; ""2.1. Instrumentation, Concentration, Solvent, and Temperature of the NMR Experiment""""2.2. Source and Preparation of the CDAs""; ""2.3. Preparation of the CDA Esters, Thioesters, and Amides""; ""2.3.1. Derivatization of Alcohols, Thiols, and Cyanohydrins Using the CDA Acid""; ""2.3.2. Derivatization of Amines Using the CDA Acid""; ""2.3.3. Preparation of the CDA Acid Chlorides""; ""2.3.4. Derivatization of Alcohols, Thiols, and Cyanohydrins Using the CDA Acid Chloride""; ""2.4. Resin-Bound CDA Derivatives (Mix-and-Shake Method)""; ""2.4.1. Preparation of Resin-Bound CDA Derivatives"" ; ""2.4.2. Preparation of Acid Chloride Resins""""2.4.3. Preparation of CDA-Resins""; ""2.4.4. Determination of the Loading of the CDA-Resins""; ""2.4.5. In-Tube Derivatization of Amines""; ""2.4.6. In-Tube Derivatization of Primary and Secondary Alcohols, Cyanohydrins, and Secondary Thiols""; ""2.4.7. In-Tube Derivatization of Amino Alcohols""; ""2.4.8. In-Tube Derivatization of Diols and Triols""; ""2.4.9. In-Tube Derivatization for Single-Derivatization Procedures""; ""3 Assignment of the Absolute Configuration of Monofunctional Compounds by Double Derivatization""
• Sommario/riassunto: This guide offers a concise explanation of the theoretical aspects necessary for understanding the methodology underpinning cutting-edge research in the field of nuclear magnetic resonance (NMR) spectroscopy.
• Titolo autorizzato: The assignment of the absolute configuration by NMR using chiral derivatizing agents
• ISBN: 0-19-046388-0; 0-19-756337-6
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910818578103321
• Lo trovi qui: Univ. Federico II
• Serie: Oxford scholarship online.