04192nam 2200709 450 991081857810332120200520144314.00-19-046388-00-19-756337-6(CKB)3710000000420275(EBL)3564608(SSID)ssj0001498482(PQKBManifestationID)12608319(PQKBTitleCode)TC0001498482(PQKBWorkID)11502285(PQKB)11183100(StDuBDS)EDZ0002341508(Au-PeEL)EBL3564608(CaPaEBR)ebr11061376(CaONFJC)MIL795807(OCoLC)932320843(MiAaPQ)EBC3564608(EXLCZ)99371000000042027520150608h20152015 uy 0engur|n|---|||||txtccrThe assignment of the absolute configuration by NMR using chiral derivatizing agents a practical guide /J.M. Seco, Emilio Quiñoá, and R. RigueraNew York, New York :Oxford University Press,2015.©20151 online resource (265 p.)Oxford scholarship onlinePreviously issued in print: 2015.0-19-999681-4 0-19-999680-6 Includes bibliographical references and index.""Cover""; ""The Assignment of the Absolute Configuration by NMR Using Chiral Derivatizing Agents""; ""Copyright""; ""Contents""; ""Preface""; ""Introduction""; ""1 The Theoretical Basis for Assignment by NMR""; ""1.1. Distinguishing Enantiomers by NMR: The Use of CDAs""; ""1.2. Structural Characteristics of the Auxiliaries and the Substrates""; ""1.3. Importance of the Conformation""; ""1.4. Importance of the Aromatic Shielding Effect""; ""1.5. Use of 13C NMR for Assignment""; ""1.6. Simplified Approaches to Assignment by NMR""""2.1. Instrumentation, Concentration, Solvent, and Temperature of the NMR Experiment""""2.2. Source and Preparation of the CDAs""; ""2.3. Preparation of the CDA Esters, Thioesters, and Amides""; ""2.3.1. Derivatization of Alcohols, Thiols, and Cyanohydrins Using the CDA Acid""; ""2.3.2. Derivatization of Amines Using the CDA Acid""; ""2.3.3. Preparation of the CDA Acid Chlorides""; ""2.3.4. Derivatization of Alcohols, Thiols, and Cyanohydrins Using the CDA Acid Chloride""; ""2.4. Resin-Bound CDA Derivatives (Mix-and-Shake Method)""; ""2.4.1. Preparation of Resin-Bound CDA Derivatives""""2.4.2. Preparation of Acid Chloride Resins""""2.4.3. Preparation of CDA-Resins""; ""2.4.4. Determination of the Loading of the CDA-Resins""; ""2.4.5. In-Tube Derivatization of Amines""; ""2.4.6. In-Tube Derivatization of Primary and Secondary Alcohols, Cyanohydrins, and Secondary Thiols""; ""2.4.7. In-Tube Derivatization of Amino Alcohols""; ""2.4.8. In-Tube Derivatization of Diols and Triols""; ""2.4.9. In-Tube Derivatization for Single-Derivatization Procedures""; ""3 Assignment of the Absolute Configuration of Monofunctional Compounds by Double Derivatization""This guide offers a concise explanation of the theoretical aspects necessary for understanding the methodology underpinning cutting-edge research in the field of nuclear magnetic resonance (NMR) spectroscopy.Oxford scholarship online.Nuclear magnetic resonance spectroscopySpectrum analysisNuclear magnetic resonance spectroscopyProblems, exercises, etcSpectrum analysisProblems, exercises, etcNuclear magnetic resonance spectroscopy.Spectrum analysis.Nuclear magnetic resonance spectroscopySpectrum analysis543/.66Seco J. M(José Manuel),1642372Quiñoá E(Emilio),Riguera R(Ricardo),MiAaPQMiAaPQMiAaPQBOOK9910818578103321The assignment of the absolute configuration by NMR using chiral derivatizing agents3987018UNINA