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Extracellular Matrix in Development / / edited by Douglas W. DeSimone, Robert Mecham



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Titolo: Extracellular Matrix in Development / / edited by Douglas W. DeSimone, Robert Mecham Visualizza cluster
Pubblicazione: Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013
Edizione: 1st ed. 2013.
Descrizione fisica: 1 online resource (259 p.)
Disciplina: 599.03
Soggetto topico: Developmental biology
Cell biology
Regenerative medicine
Tissue engineering
Cytokines
Growth factors
Stem cells
Developmental Biology
Cell Biology
Regenerative Medicine/Tissue Engineering
Cytokines and Growth Factors
Stem Cells
Persona (resp. second.): DeSimoneDouglas W
MechamRobert
Note generali: Description based upon print version of record.
Nota di bibliografia: Includes bibliographical references and index.
Nota di contenuto: Part I Informational signals in extracellular matrix and matrix influences on cell movement in the developing embryo -- Part II Extracellular matrix-direct morphogenesis, growth factor signaling, and maintenance of the stem cell niche -- Part III Model organisms and the lexicon of developmental signals associated with the extracellular matrix.
Sommario/riassunto: Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.
Titolo autorizzato: Extracellular Matrix in Development  Visualizza cluster
ISBN: 3-642-35935-3
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910739447703321
Lo trovi qui: Univ. Federico II
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Serie: Biology of Extracellular Matrix, . 0887-3224