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024 7 $a10.1007/978-3-642-35935-4
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035   $a(EBL)1106441
035   $a(OCoLC)834401615
035   $a(SSID)ssj0000878887
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035   $a(PQKBTitleCode)TC0000878887
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035   $a(DE-He213)978-3-642-35935-4
035   $a(MiAaPQ)EBC1106441
035   $a(PPN)169138933
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100   $a20130321d2013      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aExtracellular Matrix in Development /$fedited by Douglas W. DeSimone, Robert Mecham
205   $a1st ed. 2013.
210  1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2013.
215   $a1 online resource (259 p.)
225 1 $aBiology of Extracellular Matrix,$x0887-3224
300   $aDescription based upon print version of record.
311   $a3-642-42740-5 
311   $a3-642-35934-5 
320   $aIncludes bibliographical references and index.
327   $aPart I Informational signals in extracellular matrix and matrix influences on cell movement in the developing embryo -- Part II Extracellular matrix-direct morphogenesis, growth factor signaling, and maintenance of the stem cell niche -- Part III Model organisms and the lexicon of developmental signals associated with the extracellular matrix.
330   $aCells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix ? secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.
410  0$aBiology of Extracellular Matrix,$x0887-3224
606   $aDevelopmental biology
606   $aCell biology
606   $aRegenerative medicine
606   $aTissue engineering
606   $aCytokines
606   $aGrowth factors
606   $aStem cells
606   $aDevelopmental Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L18000
606   $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008
606   $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080
606   $aCytokines and Growth Factors$3https://scigraph.springernature.com/ontologies/product-market-codes/L14120
606   $aStem Cells$3https://scigraph.springernature.com/ontologies/product-market-codes/L16010
615  0$aDevelopmental biology.
615  0$aCell biology.
615  0$aRegenerative medicine.
615  0$aTissue engineering.
615  0$aCytokines.
615  0$aGrowth factors.
615  0$aStem cells.
615 14$aDevelopmental Biology.
615 24$aCell Biology.
615 24$aRegenerative Medicine/Tissue Engineering.
615 24$aCytokines and Growth Factors.
615 24$aStem Cells.
676   $a599.03
702   $aDeSimone$b Douglas W$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aMecham$b Robert$4edt$4http://id.loc.gov/vocabulary/relators/edt
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910739447703321
996   $aExtracellular Matrix in Development$93553869
997   $aUNINA