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Tumor Cell Metabolism [[electronic resource] ] : Pathways, Regulation and Biology / / edited by Sybille Mazurek, Maria Shoshan



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Titolo: Tumor Cell Metabolism [[electronic resource] ] : Pathways, Regulation and Biology / / edited by Sybille Mazurek, Maria Shoshan Visualizza cluster
Pubblicazione: Vienna : , : Springer Vienna : , : Imprint : Springer, , 2015
Edizione: 1st ed. 2015.
Descrizione fisica: 1 online resource (371 p.)
Disciplina: 610
611.01816
614.5999
616994
Soggetto topico: Cancer research
Molecular biology
Oncology  
Cancer Research
Molecular Medicine
Oncology
Persona (resp. second.): MazurekSybille
ShoshanMaria
Note generali: Description based upon print version of record.
Nota di bibliografia: Includes bibliographical references at the end of each chapters.
Nota di contenuto: Metabolic Remodeling in Bioenergetic Disorders and Cancer -- Tumor Cell Complexity and Metabolic Flexibility -- Autophagy and Tumor Cell Metabolism.-Tumour Hypoxia and the Hypoxia-Inducible Transcription -- MYC Regulation of Metabolism and Cancer -- Pyruvate Kinase M2: A Metabolic Tuner -- Role of the Pentose Phosphate Pathway in Tumour Metabolism -- Enzymes of the Tumour Metabolome in Diagnostic Applications -- Contribution of pH Alterations to the Tumor Microenvironment -- Mitochondrial Mutations in Cancer Progression: Causative, Bystanders, or Modifiers of Tumorigenesis? The Relevance of the Mitochondrial H+-ATP Synthase -- Canceromics Studies Unravel Tumor’s Glutamine Addiction -- Essential Role of Mitochondria in Pyrimidine Metabolism -- Metabolic Fluxes in Cancer Metabolism -- Targeted 13C-Labeled Tracer Fate Associations for Drug Efficacy Testing in Cancer.
Sommario/riassunto: The four sections of this book cover cell and molecular biology of tumor metabolism, metabolites, tumor microenvironment, diagnostics and epigenetics. Written by international experts, it provides a thorough insight into and understanding of tumor cell metabolism and its role in tumor biology. The book is intended for scientists in cancer cell and molecular biology, scientists in drug and diagnostic development, as well as for clinicians and oncologists.
Titolo autorizzato: Tumor Cell Metabolism  Visualizza cluster
ISBN: 3-7091-1824-7
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910298296403321
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